| Oral Pigmentations of Laugier-Hunziker Syndrome: An Important Differential Diagnosis for Peutz-Jeghers Syndrome |
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Bark Lynn Lew, Kyung Kook Hong, Sang Kil Lee, Hyo Jong Kim, Mu Hyoung Lee |
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Departments of Dermatology, and Internal Medicine, College of Medicine, Kyunghee University, Seoul, Korea
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| Laugier-Hunziker 증후군에서의 구강 색소침착 병변에 대한 고찰 |
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유박린, 홍경국, 이상길, 김효종, 이무형 |
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경희대학교 의과대학 피부과학교실, 내과학교실 |
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| Abstract |
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Oral pigmentation is seen fairly commonly in dermatologic practice. Oral pigmentation associated with Laugier-Hunziker syndrome (LHS) is an uncommon condition that shares some dermatologic features with Peutz-Jeghers syndrome (PJS). It is benign and asymptomatic, with no known cause, and is often associated with pigmentation of the nails and other mucosal surfaces. LHS and PJS show very similar skin manifestations but there age of onset, genetics, predilection site and associated systemic disease are different. However, evaluation of intestinal polyps should be performed for accurate differential diagnosis. We present seven patients whose conditions highlight the clinical syndrome known as LHS, and use the opportunity to review its clinical and pathologic features, and the relevant literature. (Intestinal Research 2005;3:145-149) |
| Key Words:
Hyperpigmentation, Laugier-Hunziker syndrome, Peutz-Jeghers syndrome |
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