Intest Res > Volume 18(1); 2020 > Article |
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FINANCIAL SUPPORT
The authors received no financial support for the research, authorship, and/or publication of this article.
AUTHOR CONTRIBUTION
Conceptualization: Grammeniatis V. Methodology: Mitselou A, Grammeniatis V, Galani V. Formal analysis: Katsanos K. Project administration: all authors. Writing - original draft: Grammeniatis V, Varouktsi A, Papadatos SS. Writing - review & editing: Mitselou A, Galani V. Approval of final manuscript: all authors
Characteristic |
IBS |
IBD |
Controls | ||||
---|---|---|---|---|---|---|---|
IBS-D | IBS-C | IBS-A | Terminal ileum | Cecum | Rectum | ||
Mean age (yr) | 44 | 54 | 43 | 35 | 38 | 46 | 46 |
Range (yr) | 19-61 | 23-66 | 40-52 | 17-61 | 24-48 | 21-60 | 18-72 |
Number | 5 | 9 | 3 | 18 | 18 | 14 | 19 |
Bowel parts, cytokines |
IBD |
IBS |
Controls |
|||
---|---|---|---|---|---|---|
Epithelium intensity | Crypts intensity | Epithelium intensity | Crypts intensity | Epithelium intensity | Crypts intensity | |
Terminal ileum | ||||||
TNF-α | 1.00a | 0.68 | 2.38b | 2.00 | 1.94b | 1.61 |
IL-6 | 2.17a | 1.89a | 1.65b | 1.22b | 1.95b | 1.70b |
IL-1β | 2.31a | 2.31a | 2.70a,b | 2.95a,b | 2.84b | 2.85b |
Cecum | ||||||
TNF-α | 0.80a | 0.80 | 2.90b | 2.35 | 2.38c | 2.00 |
IL-6 | 2.31a | 2.16a | 1.72b | 1.41b | 1.76b | 1.40b |
IL-1β | 2.65a | 2.56a | 3.05b | 3.10b | 3.25b | 2.65b |
Rectum | ||||||
TNF-α | 1.17a | 1.17 | 2.55b | 2.30 | 2.63b | 2.15b |
IL-6 | 1.87a | 2.08a | 1.73b | 1.46b | 1.55b | 1.47b |
IL-1β | 2.54a | 2.46a | 2.91b | 2.95b | 3.10b | 2.89b |
IBS subtypes |
Terminal ileum |
Cecum |
Rectum |
|||
---|---|---|---|---|---|---|
Epithelium intensity | Crypts intensity | Epithelium intensity | Crypts intensity | Epithelium intensity | Crypts intensity | |
TNF-α | ||||||
IBS-D | 2.00a | 2.00a | 2.67a | 2.00a | 2.60a | 2.20a |
IBS-C | 2.33a | 1.77 | 3.22 | 2.77 | 2.55 | 2.44 |
IBS-A | 2.33a | 2.67 | 3.00 | 3.00 | 3.00 | 2.67 |
IL-6 | ||||||
IBS-D | 1.60a | 1.00a | 1.50a | 1.50a | 3.20a | 2.00b |
IBS-C | 1.55a | 1.14a | 1.44a | 1.00a | 2.90a | 1.00a |
IBS-A | 1.77a | 1.50a | 1.67a | 1.33a | 3.00a | 1.00a |
IL-1β | ||||||
IBS-D | 3.00a | 2.60a | 2.75a | 3.00a | 3.20a | 3.00a |
IBS-C | 2.89a | 3.10a | 3.00a | 3.00a | 2.90a | 3.10a |
IBS-A | 2.67a | 3.30a | 3.00a | 3.00a | 3.00a | 3.00a |