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Intest Res > Volume 11(2); 2013 > Article
Intestinal Research 2013;11(2):127-133.
DOI: https://doi.org/10.5217/ir.2013.11.2.127    Published online April 30, 2013.
Clinical Characteristics of Lower Gastrointestinal Cancer in Crohn's Disease: Case Series of 5 Patients
Ji Min Choi, Changhyun Lee, Yoo Min Han, Minjong Lee, Dong Kee Jang, Jeehye Kwon, Jong Pil Im, Sang Gyun Kim, Joo Sung Kim, Hyun Chae Jung
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
크론병에 병발한 하부위장관계 악성종양의 임상 특성: 증례군 5예
최지민, 이창현, 한유민, 이민종, 장동기, 권지혜, 임종필, 김상균, 김주성, 정현채
Abstract
Crohn's disease is a chronic inflammatory disease that can involve the entire gastrointestinal tract. Several studies indicate that Crohn's patients with long disease duration have an increased risk of small bowel or colorectal cancer. In Korea, only a few cases of Crohn's disease-related small bowel or colorectal cancer have been reported. Here, we described 3 cases of colorectal cancer and 2 cases of small bowel cancer in patients with Crohn's disease. Among 5 patients, 3 had Crohn's disease-related lower gastrointestinal malignancy and the other 2 had sporadic lower gastrointestinal malignancies. Since the diagnosis of Crohn's disease-related lower gastrointestinal malignancy tends to be delayed, the development of malignancy should be considered in patients with long duration of Crohn's disease if patients have refractory symptoms despite intensive medical treatment. Surgical consultation should not be delayed. (Intest Res 2013;11:127-133)
Key Words: Crohn disease, Jejunal neoplasms, Ileal neoplasms, Colorectal neoplasms
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