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Intest Res > Volume 10(4); 2012 > Article
Intestinal Research 2012;10(4):397-399.
DOI: https://doi.org/10.5217/ir.2012.10.4.397    Published online October 31, 2012.
A Case of Adenocarcinoma of the Transverse Colon with Humoral Hypercalcemia of Malignancy
Jae Gon Lee, Dong Soo Han, Jae Ha Kim, You Shin Kim, Hyun Soo Kim, Jae Yoon Jeong, Ju Yeon Pyo, Yong Cheol Jeon, Joo Hyun Sohn
Departments of Internal Medicine and Pathology, Hanyang University College of Medicine, Guri, Korea
체액 면역성 고칼슘혈증을 동반한 횡행결장 선암종 1예
이재곤, 한동수, 김재하, 김유신, 김현수, 정재윤, 표주연, 전용철, 손주현
Abstract
Hypercalcemia is a common electrolyte imbalance in patients with malignancy. Approximately 80% of hypercalcemia is associated with humoral hypercalcemia of malignancy (HHM), but occurs rarely in colorectal carcinomas. A 72-year-old man was admitted with abdominal pain and bowel habit change. Colonoscopy showed a malignant tumor in the transverse colon. Laboratory data showed an elevated serum calcium level (11.6 mg/dL) and elevated parathyroid hormone-related peptide level (12.2 pmol/L). Histology showed poorly differentiated adenocarcinoma. We infused intravenous normal saline, furosemide and pamidronate. The serum calcium level was subsequently normalized. However, the patient died from cancer progression 10 days later. With a review of the relevant literature, we report a case of adenocarcinoma of the transverse colon with HHM. (Intest Res 2012;10:397-399)
Key Words: Colonic Neoplasms, Hypercalcemia, Water-Electrolyte Imbalance
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