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Intest Res > Volume 9(3); 2011 > Article
Intestinal Research 2011;9(3):225-229.
DOI:    Published online December 30, 2011.
A Case of Pyoderma Gangrenosum of the Face Associated with Ulcerative Colitis
Eun Sil Kim, Min Ho Seo, Hyuk Soon Choi, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
궤양성 대장염에 동반된 안면부 괴저성 농피증 1예
진윤태, 이홍식, 전훈재, 엄순호, 김창덕, 류호상, , , , , ,
고려대학교 의과대학 내과학교실
Ulcerative colitis is associated with various extra-intestinal manifestations, including rheumatic, dermatologic, ophthalmologic, biliary, and hematologic manifestations. Cutaneous findings are common extra-intestinal manifestations of ulcerative colitis, occurring in 10-20% of patients. Cutaneous manifestations include erythema nodosum, pyoderma gangrenosum, aphthous stomatitis, and acute febrile neutrophilic dermatosis. Treatments for these cutaneous manifestations include corticosteroids, cyclosporine, tacrolimus, mycophenolate mofetil, azathioprine, and infliximab. A 48-year-old male presented with an acute exacerbation of ulcerative colitis associated with multiple skin lesions on his face, thumbs, thighs, and feet. The final impression was neutrophilic folliculitis, which is an early form of pyoderma gangrenosum. The patient's skin lesions and colitis both improved with corticosteroids. There are rare published case reports of ulcerative colitis exacerbations associated with pyoderma gangrenosum that initiated as neutrophilic folliculitis of the face. This case report includes a review of the literature. (Intest Res 2011;9:225-229)
Key Words: Colitis, Ulcerative, Skin Manifestations, Pyoderma Gangrenosum
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