| Squamous Cell Carcinoma of the Rectum: Report of Two Cases |
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Na Rae Kim, Dong Hae Chung, Jeong Heum Baek, Yeon Ho Park, Hee Eun Kyung, Mi Sook Roh, Seung-Yeon Ha |
*Departments of Pathology, and Surgery
*Gachon University Gil Hospital, Incheon, Department of Pathology, Dong-A University School of Medicine, Busan, Korea
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| 직장에서 발생한 편평상피암종: 2증례 보고 |
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김나래, 정동해, 백정흠, 박연호, 경희은, 노미숙, 하승연 |
*가천의대길병원 병리과, 외과
*동아대학교 의과대학 병리학교실 |
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| Abstract |
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Squamous cell carcinoma of the rectum is extremely rare. Herein we report two cases of rectal squamous cell carcinoma. Case 1 was a 44-year-old Korean female presenting with abdominal pain and rectal bleeding for 3 months before her hospital visit. A colonoscopic examination revealed an ulcerated rectal mass 8 cm proximal to the anal verge. Chemoradiotherapy was administered following Hartmann's procedure in case 1. The patient remained alive during 19 months of follow up. Case 2 was a 43-year-old Korean female who had severe constipation for 2 months. A barium enema and computed tomography of the pelvis showed a rectal mass adherent to the sacrum. Based on the results of a colonoscopic biopsy, a diverting colostomy was performed in case 2, with no further treatment. The pathologic findings showed that both tumors were composed of oval-shaped cells with abundant eosinophilic cytoplasm and intercellular bridges with keratin pearls, and thus were diagnosed as well-differentiated squamous cell carcinoma. Neither of the cases showed evidence of HPV infection. The pathogenesis of rectal squamous cell carcinoma has not been clarified. Herein we report two cases of rectal squamous cell carcinoma and briefly discuss the possible histogenesis. (Intest Res 2010;8:172-176) |
| Key Words:
Rectum, Squamous Cell Carcinoma |
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