A Case of Ischemic Colitis Following Oral Osmotic Laxative for Bowel Preparation |
Chang Kyun Lee, Suck-Ho Lee, Jun Young Lee, Sang Pil Kim, Il-Kwun Chung, Sun-Joo Kim, Hyun-Deuk Cho |
Departments of Internal Medicine and Pathology, Soonchunghyang University College of Medicine, Cheonan Hospital, Cheonan, Korea
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장 정결을 위한 삼투성 완화제의 경구 복용 후 발생한 허혈성 대장염 1예 |
이창균, 이석호, 이준영, 김상필, 정일권, 김선주, 조현득 |
순천향대학교 의과대학 천안병원 내과학교실, 병리학교실 |
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Abstract |
Ischemic colitis is the most prevalent form of ischemic vascular compromise of the gastrointestinal tract. Although frequent in the elderly with co-morbidity, numerous pharmacologic agents including diuretics, pseudoephedrine, nonsteroidal anti-inflammatory drugs, oral contraceptives, and cocaine may produce colonic ischemia by mesenteric vasoconstriction. Oral hyperosmotic laxatives are frequently used as cleansing agents in bowel preparation for both radiologic and endoscopic studies. They are regarded as safe and effective agents, but can produce a rapid osmotic-mediated fluid loss, resulting in transient meseneteric hypoperfusion and subsequent ischemic colitis. Here, we describe a case of acute ischemic colitis caused by the oral osmotic laxative magnesium citrate, which was given for bowel preparation before a barium enema in a young healthy patient without underlying disease. (Intest Res 2008;6:135-139) |
Key Words:
Colitis, Ischemic, Laxatives, Colonoscopy |
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