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Intestinal Research 2008;6(1):80-84.
Published online June 30, 2008.
A Case of Pyoderma Gangrenosum Associated with Ulcerative Colitis
Young Wook Yoo, Sung Hee Jung, Yun Jung Lee, Sung Hoon Lee, Sae Hee Kim, Hyang Ie Lee, Hyeon Woong Yang, Anna Kim, Sang Woo Cha, Dong Wook Kang
Departments of Internal Medicine and Pathology and Molecular Medicine Eulji University College of Medicine, Eulji University Hospital, Daejeon, Korea
궤양성 대장염에 동반된 괴저성 농피증 1예
유영욱, 정성희, 이윤정, 이성훈, 김새희, 이향이, 양현웅, 김안나, 차상우, 강동욱
을지대학교 의과대학 을지대학병원 내과학교실, 병리학교실
Ulcerative colitis is associated with various extraintestinal manifestations. Skin lesions can occur in 9-19% of patients with ulcerative colitis. Pyoderma gangrenosum is the most severe dermatologic complication that is associated with ulcerative colitis. It is a painful, chronic ulcerating skin disease of unknown cause. The lesions usually appear on the pretibial area, but may also be found elsewhere. Diagnosis is clinical as there are no accepted histological diagnostic criteria. Systemic steroid therapy remains the treatment of choice in most patients, but various other agents have been used with occasional success including topical antibiotics, cyclosporine and infliximab. We experienced a case of pyoderma gangrenosum that developed on both pretibial areas in a 41-year-old female patient with active ulcerative colitis. The patient was treated with a corticosteroid and sulfasalazine. We report this case with a review of the literature. (Intest Res 2008;6:80-84)
Key Words: Colitis, Ulcerative, Pyoderma Gangrenosum
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