| A Case of Cytomegalovirus Colitis Complicated by Perforation after Short-term Steroid Therapy in a Patient with Eosinophilia |
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Jong Pil Im, Yoon Kyung Jeon, Sang Gyun Kim, Joo Sung Kim, Hyun Chae Jung, In Sung Song |
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Departments of Internal Medicine and Pathology, Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
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| 호산구증가증에 대한 단기간 스테로이드 치료 후 대장천공으로 발현한 거대세포바이러스 대장염 1예 |
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임종필, 전윤경, 김상균, 김주성, 정현채, 송인성 |
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서울대학교 의과대학 내과학교실 및 간연구소, 병리학교실 |
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| Abstract |
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Cytomegalovirus (CMV) infection is a rare event that has been reported mainly in immunocompromised patients who have HIV infection or receive immunosuppressive medication. Although CMV infection is generally asymptomatic in healthy individuals, CMV colitis in immunocompetent host can be potentially severe disease with significant morbidity, especially in older patients. We report a case of CMV colitis complicated by colonic perforation after short term steroid therapy in a patient with eosinophilia who has no evidence of immunosuppression. A high index of suspicion is crucial for early diagnosis of CMV colitis especially in older patients, even though obvious evidence of immunodeficiency is lacking. Colonoscopic examination including multiple biopsies is mandatory for diagnosis of CMV colitis, and antiviral agents should be started once the diagnosis is confirmed. (Intest Res 2007;5:81-86) |
| Key Words:
Cytomegalovirus, Colitis, Eosinophilia, Steroids |
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