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Intest Res > Volume 9(2); 2011 > Article
Intestinal Research 2011;9(2):158-161.
DOI: https://doi.org/10.5217/ir.2011.9.2.158    Published online August 30, 2011.
Jejunal Adenocarcinoma as Part of Metachronous Triple Primary Cancers of the Digestive Tract in Patient with Hereditary Nonpolyposis Colorectal Cancer
Mun Sun Choi, Hyun Chae Jung
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
가족성 용종성 대장암 환자에서 발생한 공장암을 포함한 소화기계의 이시성 원발성 삼중암
최문선, 정현채
서울대학교 의과대학 내과학교실, 간연구소
Abstract
Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant inherited disease characterized by onset at a relatively early age, an excess of synchronous and metachronous tumors, and a variety of extracolorectal malignancies. Small bowel carcinoma reported, is included in the tumor spectrum of HNPCC, but the frequency of occurrence of this tumor in HNPCC patients is comparatively rare. In Korea, several cases of multiple primary cancers in patients with HNPCC have been reported, however, primary jejunal adenocarcinoma in conjunction with multiple primary cancers in the digestive tract has rarely been reported. Recently, we evaluated a 61-year-old male diagnosed with metachronous triple primary cancers of the jejunum, stomach, and colon. We report this rare case of primary jejunal adenocarcinoma as a part of metachronous triple cancers along with a review of the relevant literature. (Intest Res 2011;9:158-161)
Key Words: Jejunal Cancer, Hereditary Nonpolyposis Colorectal Cancer, Multiple Primary Neoplasms, Microsatellite Instability
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