Acute cytomegalovirus (CMV) infection occurs commonly in immunocompromised and immunocompetent patients, but is usually asymptomatic in the latter. Vascular events associated with acute CMV infection have been described, but are rare. Hence, such events are rarely reported in the literature. We report a case of pulmonary embolism secondary to acute CMV colitis in an immunocompetent 78-year-old man. The patient presented with fever and diarrhea. Colonic ulcers were diagnosed based on colonoscopy findings, and CMV was the proven etiology on pathological examination. The patient subsequently experienced acute respiratory failure. Pulmonary embolism was diagnosed based on the chest radiography and computed tomography findings. A diagnosis of acute CMV colitis complicated by pulmonary embolism was made. The patient was successfully treated with intravenous administration of unfractionated heparin and intravenous ganciclovir.

Citations

Citations to this article as recorded by  

• Venous thromboembolism in infectious diseases
  Priyanka P. Nigade, Sagar S. Dhanagar, Vandana S. Nikam
  Comparative Clinical Pathology.2025; 34(3): 485.     CrossRef
• Cytomegalovirus-Induced Pericarditis, Pulmonary Embolism, and Transaminitis in an Immunocompetent Patient
  Waiz Wasey, Navpreet Badesha, Maria Rossi, Caitlin Carter, Samantha Bibee
  Cureus.2021;[Epub]     CrossRef
• Risk factors of venous thrombo-embolism during cytomegalovirus infection in immunocompetent individuals. A systematic review
  Manuela Ceccarelli, Emmanuele Venanzi Rullo, Giuseppe Nunnari
  European Journal of Clinical Microbiology & Infectious Diseases.2018; 37(3): 381.     CrossRef
• Venous thromboembolism related to cytomegalovirus infection
  Amar H. Kelkar, Kavitha S. Jacob, Eman B. Yousif, John J. Farrell
  Medicine.2017; 96(51): e9336.     CrossRef