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IBD
Management of Crohn’s disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023
Jia-Feng Wu, Hsu-Heng Yen, Horng-Yuan Wang, Ting-An Chang, Chung-Hsin Chang, Chen-Wang Chang, Te-Hsin Chao, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tzu-Chi Hsu, Tien-Yu Huang, Tsung-I Hung, Puo-Hsien Le, Chun-Che Lin, Chun-Chi Lin, Ching-Pin Lin, Jen-Kou Lin, Wei-Chen Lin, Yen-Hsuan Ni, Ming-Jium Shieh, I-Lun Shih, Chia-Tung Shun, Tzung-Jiun Tsai, Cheng-Yi Wang, Meng-Tzu Weng, Jau-Min Wong, Deng-Chyang Wu, Shu-Chen Wei
Intest Res 2024;22(3):250-285.   Published online July 29, 2024
DOI: https://doi.org/10.5217/ir.2024.00060
AbstractAbstract PDFPubReaderePub
Crohn’s disease (CD) is a chronic, fluctuating inflammatory condition that primarily affects the gastrointestinal tract. Although the incidence of CD in Taiwan is lower than that in Western countries, the severity of CD presentation appears to be similar between Asia and the West. This observation indicates the urgency for devising revised guidelines tailored to the unique reimbursement system, and patient requirements in Taiwan. The core objectives of these updated guidelines include the updated treatment choices and the integration of the treat-to-target strategy into CD management, promoting the achievement of deep remission to mitigate complications and enhance the overall quality of life. Given the diversity in disease prevalence, severity, insurance policies, and access to medical treatments in Taiwan, a customized approach is imperative for formulating these guidelines. Such tailored strategies ensure that international standards are not only adapted but also optimized to local contexts. Since the inception of its initial guidelines in 2017, the Taiwan Society of Inflammatory Bowel Disease (TSIBD) has acknowledged the importance of continuous revisions for incorporating new therapeutic options and evolving disease management practices. The latest update leverages international standards and recent research findings focused on practical implementation within the Taiwanese healthcare system.

Citations

Citations to this article as recorded by  
  • Reply to Correspondence “Early predictors of intestinal complications in pediatric-onset Crohn's disease: A long-term cohort study in Taiwan”
    Jia-Feng Wu
    Journal of the Formosan Medical Association.2026; 125(1): 112.     CrossRef
  • Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea
    Jin Hwa Park, Sang Hyoung Park, Sang Pyo Lee, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Soorack Ryu, Junwon Go
    The Korean Journal of Internal Medicine.2026; 41(1): 95.     CrossRef
  • Endoscopic and pathologic findings of esophagogastroduodenal involvement in Crohn disease in Korea: a prospective single-center cohort study
    Ga Hee Kim, Jihun Kim, Ji Yong Ahn, Sang Hyoung Park, Sung Wook Hwang, Byong Duk Ye, Hwoon-Yong Jung, Suk-Kyun Yang
    Inflammatory Bowel Diseases.2026;[Epub]     CrossRef
  • Prevalence, Clinical Characteristics, and Predictors of Difficult-to-Treat Inflammatory Bowel Disease in a Real-World Taiwanese Cohort
    Shun-Wen Hsiao, Pei-Yuan Su, Chen-Ta Yang, Yang-Yuan Chen, Hsu-Heng Yen
    Life.2026; 16(2): 197.     CrossRef
  • Annual Therapeutic Drug Monitoring in Patients with Inflammatory Bowel Disease During Infliximab Maintenance Therapy: Balancing Efficacy with Risk of Pharmacokinetic Failure
    Yujin Lim, Boram Park, Kyeongman Jeon, Ok Soon Jeong, Eun Ran Kim, Young-Ho Kim, Dong Kyung Chang, Sung Noh Hong
    Digestive Diseases and Sciences.2025; 70(8): 2804.     CrossRef
  • Impact of Obesity on the Long-Term Outcomes of Advanced Therapies in IBD: A Real-World Study in Taiwan
    Wei-Chun Hsu, Shih-Hua Lin, Chia-Jung Kuo, Horng-Yih Chiu, Chien-Ming Chen, Ming-Yao Su, Cheng-Tang Chiu, Chen-Wang Chang, Tien-Yu Huang, Yu-Bin Pan, Puo-Hsien Le
    Journal of Inflammation Research.2025; Volume 18: 7139.     CrossRef
  • Latent tuberculosis infection screening in patients with inflammatory bowel disease: a nationwide retrospective cohort study in South Korea comparing IGRA alone versus a combination of TST and IGRA
    Ye-Jee Kim, Jiyeon Kim, Jiwon Lee, Tae Sun Shim, Sang Hyoung Park, Kyung-Wook Jo
    Intestinal Research.2025; 23(4): 541.     CrossRef
  • Practices and perceptions of 5-aminosalicylic acid use in Crohn’s disease: a nationwide survey of physicians in Korea by KASID Guidelines Taskforce Team
    June Hwa Bae, Seung Yong Shin, Dong Hyun Kim, Seung Min Hong, Eun Mi Song, Ji Eun Kim, Young Joo Yang, Jiyoung Yoon, Sang-Bum Kang, Eun Soo Kim, Sung Eun Kim, Seong-Jung Kim, Jun Lee, Soo-Young Na, Soo Jung Park, Sang Hyoung Park, Won Moon, Sung-Ae Jung
    Intestinal Research.2025; 23(4): 491.     CrossRef
  • HLA-C*03:04:01 and HLA-B*15:18:01 but not HLA-DQA1*05 associated with anti- tumor necrosis factor antibody formation in Taiwanese inflammatory bowel disease patients
    Meng-Tzu Weng, Chi-Yuan Yao, Wei-Chen Lin, Sheng-Kai Lai, Chien-Chih Tung, Chun-Ying Wang, Jau-Min Wong, Pei-Lung Chen, Shu-Chen Wei
    World Journal of Gastroenterology.2025;[Epub]     CrossRef
  • 15,126 View
  • 326 Download
  • 9 Web of Science
  • 9 Crossref
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IBD
Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease updated in 2023
Hsu-Heng Yen, Jia-Feng Wu, Horng-Yuan Wang, Ting-An Chang, Chung-Hsin Chang, Chen-Wang Chang, Te-Hsin Chao, Jen-Wei Chou, Yenn-Hwei Chou, Chiao-Hsiung Chuang, Wen-Hung Hsu, Tzu-Chi Hsu, Tien-Yu Huang, Tsung-I Hung, Puo-Hsien Le, Chun-Che Lin, Chun-Chi Lin, Ching-Pin Lin, Jen-Kou Lin, Wei-Chen Lin, Yen-Hsuan Ni, Ming-Jium Shieh, I-Lun Shih, Chia-Tung Shun, Tzung-Jiun Tsai, Cheng-Yi Wang, Meng-Tzu Weng, Jau-Min Wong, Deng-Chyang Wu, Shu-Chen Wei
Intest Res 2024;22(3):213-249.   Published online July 29, 2024
DOI: https://doi.org/10.5217/ir.2023.00050
AbstractAbstract PDFPubReaderePub
Ulcerative colitis (UC) is a chronic inflammation of the gastrointestinal tract and is characterized by alternating periods of inflammation and remission. Although UC incidence is lower in Taiwan than in Western countries, its impact remains considerable, demanding updated guidelines for addressing local healthcare challenges and patient needs. The revised guidelines employ international standards and recent research, emphasizing practical implementation within the Taiwanese healthcare system. Since the inception of the guidelines in 2017, the Taiwan Society of Inflammatory Bowel Disease has acknowledged the need for ongoing revisions to incorporate emerging therapeutic options and evolving disease management practices. This updated guideline aims to align UC management with local contexts, ensuring comprehensive and context-specific recommendations, thereby raising the standard of care for UC patients in Taiwan. By adapting and optimizing international protocols for local relevance, these efforts seek to enhance health outcomes for patients with UC.

Citations

Citations to this article as recorded by  
  • Short-term and long-term outcomes of acute severe ulcerative colitis in Taiwan: a multicenter study with pre- and post-biologics comparison
    Wei-Chen Lin, Chun-Chi Lin, Wen-Hung Hsu, Feng-Fan Chiang, Chen-Wang Chang, Tzu-Chi Hsu, Deng-Chyang Wu, Horng-Yuan Wang, Jau-Min Wong, Shu-Chen Wei
    Intestinal Research.2026; 24(1): 117.     CrossRef
  • Comparison of the performance between an AI-based vision transformer and human endoscopists in predicting the endoscopic and histologic activities of ulcerative colitis
    Yuan-Yen Chang, Han-Po Yang, Yang-Yuan Chen, Hsu-Heng Yen
    DIGITAL HEALTH.2026;[Epub]     CrossRef
  • Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea
    Jin Hwa Park, Sang Hyoung Park, Sang Pyo Lee, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Soorack Ryu, Junwon Go
    The Korean Journal of Internal Medicine.2026; 41(1): 95.     CrossRef
  • Prevalence, Clinical Characteristics, and Predictors of Difficult-to-Treat Inflammatory Bowel Disease in a Real-World Taiwanese Cohort
    Shun-Wen Hsiao, Pei-Yuan Su, Chen-Ta Yang, Yang-Yuan Chen, Hsu-Heng Yen
    Life.2026; 16(2): 197.     CrossRef
  • Endoscopic Techniques for Colorectal Neoplasia Surveillance in Inflammatory Bowel Disease: A Systematic Review and Network Meta‐Analysis
    Chih‐Wen Huang, Hsu‐Heng Yen, Yang‐Yuan Chen
    United European Gastroenterology Journal.2025; 13(8): 1418.     CrossRef
  • Herpes zoster infection in patients with inflammatory bowel disease
    Dong Hyun Kim, Sang-Bum Kang
    The Korean Journal of Internal Medicine.2025; 40(3): 347.     CrossRef
  • Annual Therapeutic Drug Monitoring in Patients with Inflammatory Bowel Disease During Infliximab Maintenance Therapy: Balancing Efficacy with Risk of Pharmacokinetic Failure
    Yujin Lim, Boram Park, Kyeongman Jeon, Ok Soon Jeong, Eun Ran Kim, Young-Ho Kim, Dong Kyung Chang, Sung Noh Hong
    Digestive Diseases and Sciences.2025; 70(8): 2804.     CrossRef
  • Impact of Obesity on the Long-Term Outcomes of Advanced Therapies in IBD: A Real-World Study in Taiwan
    Wei-Chun Hsu, Shih-Hua Lin, Chia-Jung Kuo, Horng-Yih Chiu, Chien-Ming Chen, Ming-Yao Su, Cheng-Tang Chiu, Chen-Wang Chang, Tien-Yu Huang, Yu-Bin Pan, Puo-Hsien Le
    Journal of Inflammation Research.2025; Volume 18: 7139.     CrossRef
  • Serological Assessment of Hepatitis in Patients with Inflammatory Bowel Disease in Taiwan: A Retrospective Cohort Analysis
    Yueh-An Lee, Hsu-Heng Yen, Yang-Yuan Chen
    Life.2025; 15(6): 893.     CrossRef
  • Guselkumab in East Asians With Moderate‐to‐Severe Ulcerative Colitis: Subgroup Analysis of the QUASAR Induction and Maintenance Studies
    Baili Chen, Byong Duk Ye, Qian Cao, Fumihito Hirai, Masayuki Saruta, Minhu Chen, Susan Pelak, Nicole Shipitofsky, Ye Miao, Keira Herr, Bryan Wahking, Jianmin Zhuo, Tadakazu Hisamatsu
    Journal of Gastroenterology and Hepatology.2025; 40(9): 2197.     CrossRef
  • The role of vitamin D deficiency and modifiable risk factors in patients with Crohn’s disease
    Xiaoyue Feng, Qin Yin, Ying Kang, Kang Jiang, Mengqing Xu, Fangyu Wang
    Frontiers in Immunology.2025;[Epub]     CrossRef
  • Latent tuberculosis infection screening in patients with inflammatory bowel disease: a nationwide retrospective cohort study in South Korea comparing IGRA alone versus a combination of TST and IGRA
    Ye-Jee Kim, Jiyeon Kim, Jiwon Lee, Tae Sun Shim, Sang Hyoung Park, Kyung-Wook Jo
    Intestinal Research.2025; 23(4): 541.     CrossRef
  • Case Report: Cryptococcal Meningitis During Tofacitinib Therapy in Ulcerative Colitis: A Rare Opportunistic Infection
    Chien‐Ming Chen, Hsu‐Heng Yen, Yang‐Yuan Chen
    International Journal of Rheumatic Diseases.2025;[Epub]     CrossRef
  • Three Janus kinase inhibitors in ulcerative colitis: is upadacitinib taking the lead?
    Yoon Suk Jung
    Intestinal Research.2025; 23(4): 394.     CrossRef
  • Combining Network Pharmacology, Molecular Docking, and Integrative Studies to Explore the Mechanism of Helminthostachys zeylanica in Alleviating Ulcerative Colitis
    Chih‐Ting Lin, Li‐Wei Lin, Li‐Ching Chang, Lung‐Yuan Wu, Fan‐Shiu Tsai
    Food Science & Nutrition.2025;[Epub]     CrossRef
  • Acute Severe Ulcerative Colitis Patients From Asia Have Lower Colectomy Risk Than Patients From Australasia
    Richard Gareth Fernandes, Dong Hyun Kim, Leonie Ruddick-Collins, Abhinav Vasudevan, Anthony Robert Brownson, Benjamin Ngoi, Chun-Chi Lin, Craig Haifer, Dae Sung Kim, Ei Swe, Emily Kate Wright, Eun Mi Song, Gillian Mahy, Gregory Thomas Moore, Hyun Seok Lee
    Clinical Gastroenterology and Hepatology.2025;[Epub]     CrossRef
  • Prevalence and association testing of antinuclear antibodies and inflammatory bowel disease in Taiwan
    Tsai-Min Yang, Fang-Ting Lu, Hsu-Heng Yen, Yang-Yuan Chen
    PeerJ.2025; 13: e20474.     CrossRef
  • Rescue Therapies for Steroid-refractory Acute Severe Ulcerative Colitis: A Systematic Review and Network Meta-analysis
    Chih-Wen Huang, Hsu-Heng Yen, Yang-Yuan Chen
    Journal of Crohn's and Colitis.2024; 18(12): 2063.     CrossRef
  • High prevalence of vitamin D deficiency in Taiwanese patients with inflammatory bowel disease
    Chen-Ta Yang, Hsu-Heng Yen, Pei-Yuan Su, Yang-Yuan Chen, Siou-Ping Huang
    Scientific Reports.2024;[Epub]     CrossRef
  • 21,357 View
  • 438 Download
  • 17 Web of Science
  • 19 Crossref
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