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- Endoscopy
- Use of device-assisted enteroscopy in small bowel disease: an expert consensus statement by the Korean Association for the Study of Intestinal Diseases
- Han Hee Lee, Jin Su Kim, Hyeon Jeong Goong, Shin Hee Lee, Eun Hye Oh, Jihye Park, Min Cheol Kim, Kwangwoo Nam, Young Joo Yang, Tae Jun Kim, Seung-Joo Nam, Hee Seok Moon, Jae Hyun Kim, Duk Hwan Kim, Seong-Eun Kim, Seong Ran Jeon, Seung-Jae Myung, The Small Intestine Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)
- Intest Res 2023;21(1):3-19. Published online January 31, 2023
- DOI: https://doi.org/10.5217/ir.2022.00108
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Abstract
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PubReader
ePub - The introduction of device-assisted enteroscopy (DAE) in the beginning of 21st century has revolutionized the diagnosis and treatment of diseases of the small intestine. In contrast to capsule endoscopy, the other main diagnostic modality of the small bowel diseases, DAE has the unique advantages of observing the region of interest in detail and enabling tissue acquisition and therapeutic intervention. As DAE becomes an essential procedure in daily clinical practice, there is an increasing need for correct guidelines on when and how to perform it and what technical factors should be considered. In response to these needs, the Korean Association for the Study of Intestinal Diseases developed an expert consensus statement on the performance of DAE by reviewing the current evidence. This expert consensus statement particularly focuses on the indications, choice of insertion route, therapeutic intervention, complications, and relevant technical points.
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Citations
Citations to this article as recorded by
- Effect of Different Types of Antithrombotic Agents on Clinical Outcomes in Patients With Small Bowel Bleeding Who Underwent Balloon‐Assisted Enteroscopy: A KASID Multicenter Study
Jihye Park, Jin Su Kim, Joo Hye Song, Kwangwoo Nam, Seong‐Eun Kim, Eui Sun Jeong, Jae Hyun Kim, Seong Ran Jeon
Journal of Gastroenterology and Hepatology.2025; 40(2): 456. CrossRef - Balloon-assisted enteroscopy in the management of adult small-bowel intussusception: a comparative analysis of with and without double-balloon enteroscopy
Won Shik Kim, Beom Jae Lee, Moon Kyung Joo, Seung Han Kim, Jong-Jae Park
Surgical Endoscopy.2025; 39(3): 2044. CrossRef - From Data to Insights: How Is AI Revolutionizing Small-Bowel Endoscopy?
Joana Mota, Maria João Almeida, Francisco Mendes, Miguel Martins, Tiago Ribeiro, João Afonso, Pedro Cardoso, Helder Cardoso, Patrícia Andrade, João Ferreira, Miguel Mascarenhas, Guilherme Macedo
Diagnostics.2024; 14(3): 291. CrossRef - Role of Device-Assisted Enteroscopy in Crohn’s Disease
Giulia Catassi, Clelia Marmo, Antonio Gasbarrini, Maria Elena Riccioni
Journal of Clinical Medicine.2024; 13(13): 3919. CrossRef - Discordance Rate and Risk Factor of Other Diagnostic Modalities for Small Bowel Tumors Detected by Device-Assisted Enteroscopy: A Korean Association for the Study of Intestinal Disease (KASID) Multicenter Study
Jihye Park, Jin Su Kim, Joo Hye Song, Kwangwoo Nam, Seong-Eun Kim, Eui Sun Jeong, Jae Hyun Kim, Seong Ran Jeon
Gut and Liver.2024; 18(4): 686. CrossRef
- Effect of Different Types of Antithrombotic Agents on Clinical Outcomes in Patients With Small Bowel Bleeding Who Underwent Balloon‐Assisted Enteroscopy: A KASID Multicenter Study
- 8,945 View
- 226 Download
- 5 Crossref
Original Article
- Endoscopy
- Effect of gut microbiome on minor complications after a colonoscopy
- Jae Hyun Kim, Youn Jung Choi, Hye Jung Kwon, Kyoungwon Jung, Sung Eun Kim, Won Moon, Moo In Park, Seun Ja Park
- Intest Res 2021;19(3):341-348. Published online November 10, 2020
- DOI: https://doi.org/10.5217/ir.2020.00057
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Abstract
PDF
Supplementary MaterialPubReaderePub - Background/Aims
Minor complications that might occur after colonoscopy, including abdominal discomfort, bloating, diarrhea, and constipation, could a barrier for patients to undergo a screening colonoscopy. In this study, we aimed to identify the effect of gut microbial diversity and composition on minor complications after colonoscopy.
Methods
A total of 24 healthy subjects provided their stools before bowel preparation and on the 7th and 28th day after colonoscopy. On the 7th day after colonoscopy, the presence of minor complications was investigated using a questionnaire. We divided patients into 2 groups, the no complication group and complications group. The fecal microbial diversity, distribution, and composition were then compared between the groups.
Results
Five of the 24 subjects reported that they had undergone minor complications after colonoscopy. Most of the symptoms were mild and self-limited, but 1 patient needed medication. Interestingly, the Firmicutes/Bacteroidetes ratio of the initial stool samples before bowel preparation in the complication group was significantly higher than that in no complication group. After bowel preparation, the Firmicutes/Bacteroidetes ratio of the complication group decreased, but not in the no complication group. The microbial diversity of the no complication group decreased after bowel preparation, but not in the complication group.
Conclusions
The gut microbial composition and diversity before and after bowel preparation could be considered as one of the causes of minor complications after colonoscopy. Further studies are needed to delineate the role of gut microbiota in the occurrence of minor complications after colonoscopy. -
Citations
Citations to this article as recorded by- Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions
Hyeong Ho Jo, Moon Young Lee, Se Eun Ha, Dong Han Yeom, Yong Sung Kim
Clinical Endoscopy.2025; 58(1): 25. CrossRef - Depressive Symptoms and Gut Microbiota after Bowel Preparation and Colonoscopy: A Pre–Post Intervention Study
Amelia J. McGuinness, Martin O’Hely, Douglas Stupart, David Watters, Samantha L. Dawson, Christopher Hair, Michael Berk, Mohammadreza Mohebbi, Amy Loughman, Glenn Guest, Felice N. Jacka
Microorganisms.2024; 12(10): 1960. CrossRef - Benefits of Probiotic Pretreatment on the Gut Microbiota and Minor Complications after Bowel Preparation for Colonoscopy: A Randomized Double-Blind, Placebo-Controlled Pilot Trial
Dooheon Son, Youn Jung Choi, Min Young Son, Won Moon, Seun Ja Park, Sanghyun Lim, Jae Hyun Kim
Nutrients.2023; 15(5): 1141. CrossRef - Key determinants of success in fecal microbiota transplantation: From microbiome to clinic
Serena Porcari, Nicolas Benech, Mireia Valles-Colomer, Nicola Segata, Antonio Gasbarrini, Giovanni Cammarota, Harry Sokol, Gianluca Ianiro
Cell Host & Microbe.2023; 31(5): 712. CrossRef - Colonoscopy: body and psyche. Can psychiatry contribute to the quality of the examination?
Adam Zaczek, Robert Pudlo
Current Problems of Psychiatry.2023; 24: 253. CrossRef - CO2 Is Beneficial to Gut Microbiota Homeostasis during Colonoscopy: Randomized Controlled Trial
Xue Yang, Wen-Bo Xiu, Jin-Xia Wang, Liang-Ping Li, Chong He, Cai-Ping Gao
Journal of Clinical Medicine.2022; 11(18): 5281. CrossRef - Novel frontiers of agents for bowel cleansing for colonoscopy
Milena Di Leo, Andrea Iannone, Monica Arena, Giuseppe Losurdo, Maria Angela Palamara, Giuseppe Iabichino, Pierluigi Consolo, Maria Rendina, Carmelo Luigiano, Alfredo Di Leo
World Journal of Gastroenterology.2021; 27(45): 7748. CrossRef
- Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions
- 7,819 View
- 194 Download
- 6 Web of Science
- 7 Crossref
Images of the Issue
- Endoscopy
- Rectal polypoid lesion with a nodular surface
- Jae Hyun Kim
- Intest Res 2019;17(2):281-282. Published online February 7, 2019
- DOI: https://doi.org/10.5217/ir.2018.00172
- 6,017 View
- 88 Download
Original Articles
- Functional bowel disorders
- Is stool frequency associated with the richness and community composition of gut microbiota?
- Hye Jung Kwon, Jong Hyun Lim, Dongmin Kang, Sanghyun Lim, Seun Ja Park, Jae Hyun Kim
- Intest Res 2019;17(3):419-426. Published online February 7, 2019
- DOI: https://doi.org/10.5217/ir.2018.00149
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Abstract
PDFSupplementary MaterialPubReaderePub
- Background/Aims
Recently, a number of studies have reported that the gut microbiota could contribute to human conditions, including obesity, inflammation, cancer development, and behavior. We hypothesized that the composition and distribution of gut microbiota are different according to stool frequency, and attempted to identify the association between gut microbiota and stool frequency.
Methods
We collected fecal samples from healthy individuals divided into 3 groups according to stool frequency: group 1, a small number of defecation (≤2 times/wk); group 2, normal defecation (1 time/day or 1 time/2 day); and group 3, a large number of defecation (≥2–3 times/day). We evaluated the composition and distribution of the gut microbiota in each group via 16S rRNA-based taxonomic profiling of the fecal samples.
Results
Fecal samples were collected from a total of 60 individuals (31 men and 29 women, aged 34.1±5.88 years), and each group comprised 20 individuals. The microbial richness of group 1 was significantly higher than that of group 3 and tended to decrease with increasing number of defecation (P<0.05). The biological community composition was fairly different according to the number of defecation, and Bacteroidetes to Firmicutes ratio was higher in group 1 than in the other groups. Moreover, we found specific strains at the family and genus levels in groups 1 and 3.
Conclusions
Bacteroidetes to Firmicutes ratio and the abundance of Bifidobacterium were different according to the stool frequency, and specific bacteria were identified in the subjects with large and small numbers of defecation, respectively. These findings suggest that stool frequency might be associated with the richness and community composition of the gut microbiota. -
Citations
Citations to this article as recorded by- Bowel movement alterations predict the severity of diverticular disease and the risk of acute diverticulitis: a prospective, international study
Antonio Tursi, Daniele Piovani, Giovanni Brandimarte, Francesco Di Mario, Walter Elisei, Marcello Picchio, Gisella Figlioli, Gabrio Bassotti, Leonardo Allegretta, Maria Laura Annunziata, Mauro Bafutto, Maria Antonia Bianco, Raffaele Colucci, Rita Coniglia
Intestinal Research.2025; 23(1): 96. CrossRef - Personalized probiotic strategy considering bowel habits: impacts on gut microbiota composition and alleviation of gastrointestinal symptoms via Consti-Biome and Sensi-Biome
Uigi Min, Yoo-Jeong Jin, You Jin Jang, Jonghyun Lim, Byung-Yong Kim
Frontiers in Nutrition.2024;[Epub] CrossRef - Deciphering the Impact of Defecation Frequency on Gut Microbiome Composition and Diversity
Gwoncheol Park, Seongok Kim, WonJune Lee, Gyungcheon Kim, Hakdong Shin
International Journal of Molecular Sciences.2024; 25(9): 4657. CrossRef - Advancing human gut microbiota research by considering gut transit time
Nicola Procházková, Gwen Falony, Lars Ove Dragsted, Tine Rask Licht, Jeroen Raes, Henrik M Roager
Gut.2023; 72(1): 180. CrossRef - Gut Microbiome Analysis for Personalized Nutrition: The State of Science
Marie‐Christine Simon, Christian Sina, Paola G. Ferrario, Hannelore Daniel
Molecular Nutrition & Food Research.2023;[Epub] CrossRef - The gut-microbiota-brain axis in a Spanish population in the aftermath of the COVID-19 pandemic: microbiota composition linked to anxiety, trauma, and depression profiles
Stefanie Malan-Müller, Mireia Valles-Colomer, Tomás Palomo, Juan C. Leza
Gut Microbes.2023;[Epub] CrossRef - Fecal microbiota transplantation in Parkinson's disease—A randomized repeat-dose, placebo-controlled clinical pilot study
Herbert L. DuPont, Jessika Suescun, Zhi-Dong Jiang, Eric L. Brown, Heather T. Essigmann, Ashley S. Alexander, Andrew W. DuPont, Tehseen Iqbal, Netanya S. Utay, Michael Newmark, Mya C. Schiess
Frontiers in Neurology.2023;[Epub] CrossRef - Effect of Probiotic-Fortified Infant Formula on Infant Gut Health and Microbiota Modulation
Ju Young Eor, Chul Sang Lee, Sung Ho Moon, Ju Young Cheon, Duleepa Pathiraja, Byeonghyeok Park, Min Jae Shin, Jae-Young Kim, Sangjong Kim, Youngbae Noh, Yunhan Kim, In-Geol Choi, Sae Hun Kim
Food Science of Animal Resources.2023; 43(4): 659. CrossRef - Efficacy of washed microbiota transplantation for therapeutic targets of refractory functional constipation and the influencing factors: a single-center, retrospective, 24-week follow-up study
Liquan Wu, Qingfen Yuan, Lihao Wu, Harry Hua-Xiang Xia, Muxiao Zhong, Tao Liu, Xiaoyan Ye, Danping Luo, Jiating Xu, Wenrui Xie, Xingxiang He, Jieyi Cai
BMC Gastroenterology.2023;[Epub] CrossRef - Scarring the early-life microbiome: its potential life-long effects on human health and diseases
Hyunji Park, Na-Young Park, Ara Koh
BMB Reports.2023; 56(9): 469. CrossRef - Frequency of Bowel Movements and Risk of Diverticulitis
Manol Jovani, Wenjie Ma, Kyle Staller, Amit D. Joshi, Po-Hong Liu, Long H. Nguyen, Paul Lochhead, Yin Cao, Idy Tam, Kana Wu, Edward L. Giovannucci, Lisa L. Strate, Andrew T. Chan
Clinical Gastroenterology and Hepatology.2022; 20(2): 325. CrossRef - Association Between Gastrointestinal Symptoms and Depression in a Representative Sample of Adults in the United States: Findings From National Health and Nutrition Examination Survey (2005–2016)
Sarah J. Eustis, Michael W. McCall, E. Angela Murphy, Michael D. Wirth
Journal of the Academy of Consultation-Liaison Psychiatry.2022; 63(3): 268. CrossRef - Effects of probiotics on cognitive and emotional functions in healthy older adults: Protocol for a double‐blind randomized placebo‐controlled crossover trial
Cristofer Ruiz‐Gonzalez, Diana Cardona, Miguel Rodriguez‐Arrastia, Carmen Ropero‐Padilla, Lola Rueda‐Ruzafa, Francisca Carvajal, Nuria Sanchez‐Labraca, Adrian Aparicio Mota, Pablo Roman
Research in Nursing & Health.2022; 45(3): 274. CrossRef - Diet and Gut Microbiome and the “Chicken or Egg” Problem
Hannelore Daniel
Frontiers in Nutrition.2022;[Epub] CrossRef - Proposal of a health gut microbiome index based on a meta-analysis of Korean and global population datasets
Hyun-Seok Oh, Uigi Min, Hyejin Jang, Namil Kim, Jeongmin Lim, Mauricio Chalita, Jongsik Chun
Journal of Microbiology.2022; 60(5): 533. CrossRef - Physical Complaints Decrease after Following a Few-Foods Diet in Children with ADHD
Lidy Pelsser, Tim Stobernack, Klaas Frankena
Nutrients.2022; 14(15): 3036. CrossRef - Differences in gut microbiota correlate with symptoms and regional brain volumes in patients with late-life depression
Chia-Fen Tsai, Chia-Hsien Chuang, Yen-Po Wang, Ya-Bo Lin, Pei-Chi Tu, Pei-Yi Liu, Po-Shan Wu, Chung-Yen Lin, Ching-Liang Lu
Frontiers in Aging Neuroscience.2022;[Epub] CrossRef - A Clinical Outcome of the Anti-PD-1 Therapy of Melanoma in Polish Patients Is Mediated by Population-Specific Gut Microbiome Composition
Bernadeta Pietrzak, Katarzyna Tomela, Agnieszka Olejnik-Schmidt, Łukasz Galus, Jacek Mackiewicz, Mariusz Kaczmarek, Andrzej Mackiewicz, Marcin Schmidt
Cancers.2022; 14(21): 5369. CrossRef - Nutritional, Health and Lifestyle Status of a Highly Physically Active and Health-Conscious Long-Term Vegan Man: A Case Report from Slovenia
Boštjan Jakše, Stanislav Pinter
Reports.2022; 5(4): 45. CrossRef - Self-Perception of Changes in Routines in Adults and Older Adults Associated to Social Distancing Due to COVID-19—A Study in São Paulo, Brazil
Adriana Machado-Lima, Angélica Castilho Alonso, Débora Gozzo, Gisele Garcia Zanca, Guilherme Carlos Brech, José Maria Montiel, Marta Ferreira Bastos, Priscila Larcher Longo, Sandra Regina Mota-Ortiz
Frontiers in Psychology.2021;[Epub] CrossRef - Changes in gut microbiota in the acute phase after spinal cord injury correlate with severity of the lesion
Gabriele Bazzocchi, Silvia Turroni, Maria Chiara Bulzamini, Federica D’Amico, Angelica Bava, Mirco Castiglioni, Valentina Cagnetta, Ernesto Losavio, Maurizio Cazzaniga, Laura Terenghi, Luisa De Palma, Giuseppina Frasca, Beatrice Aiachini, Sonia Cremascoli
Scientific Reports.2021;[Epub] CrossRef - Stool pattern is associated with not only the prevalence of tumorigenic bacteria isolated from fecal matter but also plasma and fecal fatty acids in healthy Japanese adults
Daiki Watanabe, Haruka Murakami, Harumi Ohno, Kumpei Tanisawa, Kana Konishi, Kikue Todoroki-Mori, Yuta Tsunematsu, Michio Sato, Yuji Ogata, Noriyuki Miyoshi, Naoto Kubota, Jun Kunisawa, Keiji Wakabayashi, Tetsuya Kubota, Kenji Watanabe, Motohiko Miyachi
BMC Microbiology.2021;[Epub] CrossRef - Shifts in the Fecal Microbial Community of Cystoisospora suis Infected Piglets in Response to Toltrazuril
Aruna Shrestha, Barbara U. Metzler-Zebeli, Hamadi Karembe, Daniel Sperling, Simone Koger, Anja Joachim
Frontiers in Microbiology.2020;[Epub] CrossRef - Diet and the gut microbiome: from hype to hypothesis
Hannelore Daniel
British Journal of Nutrition.2020; 124(6): 521. CrossRef - The Microbiota Profile in Inflamed and Non-Inflamed Ileal Pouch–Anal Anastomosis
Sabrina Just Kousgaard, Thomas Yssing Michaelsen, Hans Linde Nielsen, Karina Frahm Kirk, Mads Albertsen, Ole Thorlacius-Ussing
Microorganisms.2020; 8(10): 1611. CrossRef
- Bowel movement alterations predict the severity of diverticular disease and the risk of acute diverticulitis: a prospective, international study
- 12,778 View
- 258 Download
- 26 Web of Science
- 25 Crossref
- Colorectal neoplasia
- Clinical significance of carcinoembryonic antigen in peritoneal fluid detected during operation in stage I–III colorectal cancer patients
- Jae Hyun Kim, Seunghun Lee, Seung Hyun Lee, Byung Kwon Ahn, Sung Uhn Baek, Won Moon, Seun Ja Park
- Intest Res 2018;16(3):467-474. Published online July 27, 2018
- DOI: https://doi.org/10.5217/ir.2018.16.3.467
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Abstract
PDFPubReaderePub
<b>Background/Aims</b><br/> Early diagnosis of peritoneal metastases in patients with colorectal cancer (CRC) can influence patient prognosis. The aim of this study was to identify the clinical significance of carcinoembryonic antigen (CEA) in peritoneal fluid detected during operation in stage I–III CRC patients.
Methods Between April 2009 and April 2015, we reviewed medical records from a total of 60 stage I–III CRC patients who had peritoneal fluid collected during operation. Patients who had positive cytology in the assessment of peritoneal fluid were excluded. We evaluated the values of CEA in peritoneal fluid (pCEA) to predict the long-term outcomes of these patients using Kaplan-Meier curves and Cox regression models.
Results The median follow-up duration was 37 months (interquartile range, 21–50 months). On receiver operating characteristic analysis, pCEA had the largest area under the curve (0.793; 95% confidence interval, 0.635–0.950;
P =0.001) with an optimal cutoff value of 26.84 (sensitivity, 80.0%; specificity, 76.6%) for predicting recurrence. The recurrence rate was 8.1% in patients with low pCEA (<26.84 ng/mL, n=37), and 52.2% in patients with high pCEA (≥26.84 ng/mL, n=23). In multivariate Cox regression analysis, high pCEA (≥26.84 ng/mL) was a risk factor for poor cancer-free survival (CFS) in stage I–III patients.Conclusions In this study, we determined that high pCEA (≥26.84 ng/mL) detected during operation was helpful for the prediction of poor CFS in patients with stage I–III CRC.
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Citations
Citations to this article as recorded by- Evaluation of peritoneal Carcinoembryonic Antigen as a survival prognostic factor in gastric cancer patients: a single western center experience
Nicola Natalizi, Elisabetta Marino, Luigina Graziosi, Annibale Donini
Updates in Surgery.2023; 75(5): 1211. CrossRef - Prognostic Significance of Preoperative Serum Carcinoembryonic Antigen Varies with Lymph Node Metastasis Status in Colorectal Cancer
Jing Jia, MinZhe Li, Wenhao Teng, Lin Wang, Weidong Zang, Jun Xiao, Ying Chen, Dan Zhao
Journal of Oncology.2021; 2021: 1. CrossRef
- Evaluation of peritoneal Carcinoembryonic Antigen as a survival prognostic factor in gastric cancer patients: a single western center experience
- 9,530 View
- 87 Download
- 2 Web of Science
- 2 Crossref
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