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Original Articles
The Effect of Indigocarmine on Improvement of the Polyp Detection Rate during Colonoscopic Examination with Hood Cap
Sang Chang Kwon, Sung Won Choi, Seong Ho Choi, Hee Seung Park, Seung Heon Lee, Bong Gun Kim, Eun Hee Seo, Mun Jang, Seung Min Ryu, Dong Hyun Kim, Young Hoon Kim, Jun Ouk Ha, Jae Seung Lee
Intest Res 2014;12(1):60-65.   Published online January 28, 2014
DOI: https://doi.org/10.5217/ir.2014.12.1.60
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

Hood cap-assisted chromocolonoscopy using indigocarmine is expected to improve the detection rate of colorectal polyps, especially adenomatous polyps. Therefore, aim of the present study was to evaluate the usefulness of hood cap-assisted chromocolonoscopy in routine colonoscopic examinations.

Methods

From January, 2013 through March, 2013, a total of 86 patients were enrolled (M:F=33:53, mean age=60 years). For each patient, hood cap-assisted colonoscopic examination was performed, followed by hood cap-assisted chromocolonoscopy using 0.2% indigocarmine from the cecum to the hepatic flexure. Total numbers and characteristics of polyps were compared before and after indigo carmine dye spraying.

Results

Prior to dye spraying, 48 polyps were found in 37 patients, and after dye spraying, 53 additional polyps were found in 34 patients. Of these undetected polyps, 45 (85%) were small sized polyps (≤0.5 cm). Histologically, 19 (36%) were adenomatous polyps, and of these, 15 (28%) were tubular adenomas and 4 (8%) were serrated adenomas. As for the polyp detection rate, there was no difference between the expert and the non-expert groups.

Conclusion

Hood cap-assisted chromocolonoscopic examination using indigocarmine was helpful in detecting cecum and ascending colon polyps, especially small sized polyps (<0.5 cm) and neoplastic polyps.

Citations

Citations to this article as recorded by  
  • Risk factors for peritonitis in patients on continuous ambulatory peritoneal dialysis who undergo colonoscopy: a retrospective multicentre study
    Tae-Geun Gweon, Sung Hoon Jung, Sang Woo Kim, Kang-Moon Lee, Dae Young Cheung, Bo-In Lee, Hwang Choi
    BMC Gastroenterology.2019;[Epub]     CrossRef
  • A prospective randomized comparative study of cold forceps polypectomy by using narrow-band imaging endoscopy versus cold snare polypectomy in patients with diminutive colorectal polyps
    Soo-kyung Park, Bong Min Ko, Jae Pil Han, Su Jin Hong, Moon Sung Lee
    Gastrointestinal Endoscopy.2016; 83(3): 527.     CrossRef
  • Is Retroflexion Helpful in Detecting Adenomas in the Right Colon?: A Single Center Interim Analysis
    Hyun Seok Lee, Seong Woo Jeon
    Intestinal Research.2015; 13(4): 326.     CrossRef
  • Detection of Polyps Including Adenomas in the Ascending Colon by Cap-assisted Chromocolonoscopy with Indigo Carmine
    Hyun Seok Lee
    Intestinal Research.2014; 12(1): 3.     CrossRef
  • 14,389 View
  • 47 Download
  • 3 Web of Science
  • 4 Crossref
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Comparison of the Efficacy and Tolerability between Same-day Picosulfate and Split-dose Polyethylene Glycol Bowel Preparation for Afternoon Colonoscopy: A Prospective, Randomized, Investigator-blinded Trial
Mi Seon Kang, Tae Oh Kim, Eun Hee Seo, Da Kyung Jung, Mo Se Kim, Nae Yun Heo, Jong Ha Park, Seung Ha Park, Young Soo Moon
Intest Res 2014;12(1):53-59.   Published online January 28, 2014
DOI: https://doi.org/10.5217/ir.2014.12.1.53
AbstractAbstract PDFPubReader
<b>Background/Aims</b><br/>

In the present study, we evaluated the efficacy and tolerability between same-day bowel preparation protocols using 2 sachets of Picosulfate and a 4 L split-dose polyethylene glycol (PEG) bowel preparation for afternoon colonoscopy.

Methods

The study had a single-center, prospective, randomized, and investigator-blinded, non-inferiority design. We evaluated bowel preparation quality according to the Ottawa scale, patient tolerability, compliance, incidence of adverse events, sleep quality, and polyp/adenoma detection rate.

Results

Among the 196 patients analyzed (mean age, 55.3 years; 50.3% men), 97 received the same-day regimen of 2 sachets of picosulfate (group A) and 99 received the 4 L split-dose PEG regimen (group B). The Ottawa score of the total colon was 4.05±1.56 in group A and 3.80±1.55 in group B (P=0.255). The proportion of patients having adequate bowel preparation in the same-day picosulfate group (61.5%) was slightly less than the 4 L PEG group (71.3%); however, the difference was not statistically significant (P=0.133). Tolerability of the group A regimen was superior to that of the group B regimen (P<0.000). The same-day picosulfate regimen was associated with fewer adverse events, such as abdominal bloating (P=0.037) and better sleep quality (P<0.000).

Conclusions

The same-day picosulfate regimen and the 4 L split-dose PEG regimen had similar efficacy in bowel preparation for afternoon colonoscopy. However, the same-day picosulfate regimen was easier to administer, produced fewer adverse events, and enabled better sleep quality.

Citations

Citations to this article as recorded by  
  • Efficacy and safety of same‐day preparation with sodium picosulfate plus magnesium citrate on the day of colonoscopy for bowel preparation: Multicenter, single‐arm, open‐label study
    Hitomi Hori, Nobuaki Ikezawa, Shinwa Tanaka, Chise Ueda, Mizuho Fujisawa, Shinya Hoki, Hiroshi Tanabe, Ryosuke Ishida, Norihiro Okamoto, Hiroshi Takayama, Haruka Miyazaki, Hiroya Sakaguchi, Masato Kinoshita, Hirofumi Abe, Tetsuya Yoshizaki, Makoto Ooi, Ma
    Journal of Gastroenterology and Hepatology.2024; 39(10): 2151.     CrossRef
  • Comparison Between Same-Day and Split-Dose Preparations with Sodium Picosulfate/Magnesium Citrate: A Randomized Noninferiority Study
    Chen-Ta Yang, Hsuan-Yuan Huang, Hsu-Heng Yen, Chia-Wei Yang, Yang-Yuan Chen, Siou-Ping Huang
    Digestive Diseases and Sciences.2022; 67(8): 3964.     CrossRef
  • Efectividad y tolerabilidad de tres tipos de productos de preparación para colonoscopia
    Luis Fernando Roldán Molina, Lina María Roldán Delfino, Sandra Milena León Ramírez, Edilberto Elías Nuñez Cabarcas, Hilda María Pérez Useche, Antonio José Restrepo Peláez, María Adelaida Saffón Abad, Julio Eduardo Zuleta Muñoz, Juan Nicolás Zuluaga Aguila
    Revista colombiana de Gastroenterología.2021; 36(3): 334.     CrossRef
  • A prospective randomized clinical study evaluating the efficacy and compliance of oral sulfate solution and 2-L ascorbic acid plus polyethylene glycol
    Ki Hwan Kwon, Ji Ae Lee, Yun Jeong Lim, Beom Jae Lee, Moon Kyung Joo, Yu Ra Sim, Wonjae Choi, Taehyun Kim, Ji Yoon Kim, Ei Rie Cho, Yoon Tae Jeen, Jong-Jae Park
    The Korean Journal of Internal Medicine.2020; 35(4): 873.     CrossRef
  • A randomized controlled trial on comparison of colon cleansing for colonoscopy bowel preparation using one-day or two-day regimen methods
    Saleh Azadbakht, Morteza Azadbakht, Salehe Azadbakht, Alireza Esmaili, Parisa Rahmani
    International Journal of Surgery Open.2020; 27: 140.     CrossRef
  • Split-dose vs same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials
    Nasim Parsa, Eric A Grisham, Courtney J Cockerell, Michelle L Matteson-Kome, Ramakrishna V Bysani, Sami Samiullah, Douglas L Nguyen, Veysel Tahan, Yezaz A Ghouri, Srinivas R Puli, Matthew L Bechtold
    World Journal of Meta-Analysis.2020; 8(6): 461.     CrossRef
  • Split-dose vs same-day bowel preparation for afternoon colonoscopies: A meta-analysis of randomized controlled trials
    Nasim Parsa, Eric A Grisham, Courtney J Cockerell, Michelle L Matteson-Kome, Ramakrishna V Bysani, Sami Samiullah, Douglas L Nguyen, Veysel Tahan, Yezaz A Ghouri, Srinivas R Puli, Matthew L Bechtold
    World Journal of Meta-Analysis.2020; 8(6): 462.     CrossRef
  • Same-Day Regimen as an Alternative to Split Preparation for Colonoscopy: A Systematic Review with Meta-Analysis
    Cristina Bucci, Fabiana Zingone, Pietro Schettino, Clelia Marmo, Riccardo Marmo
    Gastroenterology Research and Practice.2019; 2019: 1.     CrossRef
  • The Efficacy of Split-Dose Bowel Preparations for Polyp Detection: A Systematic Review and Meta-Analysis
    Kathleen Zawaly, Colin Rumbolt, Ahmed M. Abou-Setta, Christine Neilson, Rasheda Rabbani, Ryan Zarychanski, Harminder Singh
    American Journal of Gastroenterology.2019; 114(6): 884.     CrossRef
  • Comparison of Bowel Cleansing Efficacy, Safety, Bowel Movement Kinetics, and Patient Tolerability of Same-Day and Split-Dose Bowel Preparation Using 4 L of Polyethylene Glycol: A Prospective Randomized Study
    Myeongsook Seo, Tae-Geun Gweon, Cheal Wung Huh, Jeong Seon Ji, Hwang Choi
    Diseases of the Colon & Rectum.2019; 62(12): 1518.     CrossRef
  • Same-day Versus Split-dose Bowel Preparation Before Colonoscopy
    Yuan-Lung Cheng, Kuang-Wei Huang, Wei-Chih Liao, Jiing-Chyuan Luo, Keng-Hsin Lan, Chien-Wei Su, Yuan-Jen Wang, Ming-Chih Hou
    Journal of Clinical Gastroenterology.2018; 52(5): 392.     CrossRef
  • Polyp detection rate may predict adenoma detection rate: a meta-analysis
    Yaron Niv
    European Journal of Gastroenterology & Hepatology.2018; 30(3): 247.     CrossRef
  • Bowel Preparations Administered the Morning of Colonoscopy Provide Similar Efficacy to a Split Dose Regimen
    Danny J. Avalos, Fernando J. Castro, Marc J. Zuckerman, Tara Keihanian, Andrew C. Berry, Benjamin Nutter, Daniel A. Sussman
    Journal of Clinical Gastroenterology.2018; 52(10): 859.     CrossRef
  • Sodium picosulphate or polyethylene glycol before elective colonoscopy in outpatients? A systematic review and meta-analysis
    Rodrigo Silva de Paula Rocha, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Wanderley Marques Bernardo, Maurício Kazuyoshi Minata, Flávio Hiroshi Ananias Morita, Júlio Cesar Martins Aquino, Elisa Ryoka Baba, Nelson Tomio Miyajima, Eduardo Guimarãe
    World Journal of Gastrointestinal Endoscopy.2018; 10(12): 422.     CrossRef
  • Low Volume Polyethylene Glycol (PEG) Plus Ascorbic Acid, a Valid Alternative to Standard PEG
    Su Hwan Kim, Ji Won Kim
    Gut and Liver.2016; 10(2): 160.     CrossRef
  • Patient Descriptions of Rectal Effluents May Help to Predict the Quality of Bowel Preparation With Photographic Examples
    Hoonsub So, Sun-Jin Boo, Hyungil Seo, Ho-Su Lee, Hyojeong Lee, Sang Hyoung Park, Kyung-Jo Kim, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Jin-Ho Kim, Seungbong Han, Dong-Hoon Yang
    Intestinal Research.2015; 13(2): 153.     CrossRef
  • Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate
    Seong Ran Jeon, Hyun Gun Kim, Ji Seong Lee, Jin-Oh Kim, Tae Hee Lee, Jun-Hyung Cho, Yong Hun Kim, Joo Young Cho, Joon Seong Lee
    International Journal of Colorectal Disease.2015; 30(2): 251.     CrossRef
  • Colon Transit Time May Predict Inadequate Bowel Preparation in Patients With Chronic Constipation
    Hong Jun Park, Myeong Hun Chae, Hyun-Soo Kim, Jae Woo Kim, Moon Young Kim, Soon Koo Baik, Sang Ok Kwon, Hee Man Kim, Kyong Joo Lee
    Intestinal Research.2015; 13(4): 339.     CrossRef
  • Bowel Preparation, the First Step for a Good Quality Colonoscopy
    Ho-Su Lee, Jeong-Sik Byeon
    Intestinal Research.2014; 12(1): 1.     CrossRef
  • 7,498 View
  • 57 Download
  • 16 Web of Science
  • 19 Crossref
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Case Report
Ulcerative Colitis Complicating Pseudomembranous Colitis of the Right Colon
Hee Rin Joo, Tae Oh Kim, Tae Gyoon Kim, Eun Hee Seo, Jongha Park, Seung Ha Park, Sung Yeon Yang, Young Soo Moon
Intest Res 2011;9(2):144-147.   Published online August 30, 2011
DOI: https://doi.org/10.5217/ir.2011.9.2.144
AbstractAbstract PDF
Clostridium difficile (C. difficile) is a cytotoxin-producing anaerobic gram-positive rod that is responsible for pseudomembranous colitis (PMC). The incidence of C. difficile is increasing in ulcerative colitis (UC) and inflammatory bowel disease patients and is associated with a more severe course, a longer hospital stay, higher financial costs, a greater likelihood of colectomy, and high mortality. PMC may occur anywhere along the intestinal tract, but it is often found in the distal colon. PMC involving the proximal colon with rectosigmoid sparing is rarely reported in patients with UC. We describe the case of a 35-year-old woman in remission from UC who presented with frequent diarrhea and abdominal pain. She was treated with ciprofloxacin for infectious enterocolitis at a local hospital; however, her symptoms did not improve. A colonoscopy revealed yellow-white plaques with edematous, erythematous from the proximal ascending colon to the cecum, and feces positive for C. difficile toxin. She was treated with metronidazole (500 mg, three times a day) for two weeks, and improved rapidly. Physicians should carefully examine the entire colon via colonoscopy, and perform stool exams for C. difficile in patients with UC who have been treated with antibiotics and in those who develop prolonged diarrhea despite medical treatment. (Intest Res 2011;9:144-147)
  • 3,257 View
  • 21 Download
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