Intestinal Research

Reviews

IBD

Effect of resistance exercise training on Crohn’s disease patients: Konstantinos Papadimitriou; Intest Res 2021;19(3):275-281. Published online November 20, 2020; DOI: https://doi.org/10.5217/ir.2020.00043

Crohn’s disease (CD) is observed with increased levels of cytokines which cause inflammation in many parts of the digestive tract. Aerobic exercise contributes to the reduction of the intestine’s inflammation and increases the quality of life. Another type of exercise that shows research interest about its effects on CD symptoms is the resistance exercise (RE). The aim of the study was to review the influence of RE on CD patients. The study’s literature was collected from PubMed and Scholar databases. According to the results, the main phase of a RE training program must have a gradual increase of intensity (60%–80%) and resting periods of 15–30 seconds after each exercise, and 2–3 minutes between exercises. Also, CD patients who were in remission improved the muscle strength and quality of life via their participation in RE training program. However, the secretion of interleukin-6 in both CD and RE contributes in various physiological mechanisms setting a contradictory role in the effectiveness of RE at the disease’s inflammatory situation. So, the use of RE training in CD patients needs more research for safer participation.

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Association of habitual physical activity with depression and anxiety: a multicentre cross-sectional study
Sitong Liu, Yunting Mei, Li Huang, Xudong Liu, Yuandi Xi
BMJ Open.2024; 14(1): e076095. CrossRef
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S. V. Kostyukevich, I. G. Bakulin
Koloproktologia.2024; 23(1): 152. CrossRef
Analysis of current situation and influencing factors of marital adjustment in patients with Crohn’s disease and their spouses
Ting Pan, Danlei Chen, Zhihui Yu, Qing Liu, Yan Chen, Ailing Zhang, Fang Kong
Medicine.2024; 103(11): e37527. CrossRef
Progress in research of exercise intervention in inflammatory bowel disease
Shao-Peng Sun, Jia-Jia Chen, Ming-Xu Zheng, Yi-Hong Fan, Bin Lv
World Chinese Journal of Digestology.2024; 32(5): 339. CrossRef
Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease

Advances in Geriatric Medicine and Research.2024;[Epub] CrossRef
Impact of Different Nutrition Strategies on Patients with Inflammatory Bowel Disease (IBD)
Konstantinos Papadimitriou, Sousana K. Papadopoulou
Nutrients.2023; 15(4): 1056. CrossRef
Nutritional Risk and Sarcopenia Features in Patients with Crohn’s Disease: Relation to Body Composition, Physical Performance, Nutritional Questionnaires and Biomarkers
Konstantinos Papadimitriou, Paraskevi Detopoulou, Konstantinos Soufleris, Gavriela Voulgaridou, Despoina Tsoumana, Panagiotis Ntopromireskou, Constantinos Giaginis, Ioanna P. Chatziprodromidou, Maria Spanoudaki, Sousana K. Papadopoulou
Nutrients.2023; 15(16): 3615. CrossRef
A Repeated Cross-Sectional Pilot Study of Physical Activity, Levels of Depression and Anxiety during the COVID-19 Pandemic in Young Greek Adults
Smaragda Skalidou, Andreas Anestis, Emmanouil Skalidis, Ourania Kontaxi, Athanasia Kyrezi, Panagiota Konstantinou, Konstantinos Papadimitriou
Healthcare.2023; 11(18): 2493. CrossRef
Attitude and influencing factors on exercise in patients with moderately to severely active inflammatory bowel disease: a qualitative study
Jing Wang, Shuping Tong, Yuehong Niu, Bingqing Lu
BMJ Open.2023; 13(12): e080084. CrossRef
The Influence of Aerobic Type Exercise on Active Crohn’s Disease Patients: The Incidence of an Elite Athlete
Konstantinos Papadimitriou
Healthcare.2022; 10(4): 713. CrossRef
Evaluación de actividad física como coadyuvante terapéutico para pacientes con enfermedad inflamatoria intestinal: una revisión.
Diego Fernández-Lázaro, Nuria Hernández-Burgos, Raúl Cobreros Mielgo, Sandra García-Lázaro
Investigación Clínica.2022; 63(3): 304. CrossRef
Acute Low-Intensity Treadmill Running Upregulates the Expression of Intestinal Glucose Transporters via GLP-2 in Mice
Kai Aoki, Takuji Suzuki, Fang Hui, Takuro Nakano, Koki Yanazawa, Masato Yonamine, Shinichiro Fujita, Takehito Sugasawa, Yasuko Yoshida, Naomi Omi, Yasushi Kawakami, Kazuhiro Takekoshi
Nutrients.2021; 13(5): 1735. CrossRef

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IBD

Management of Clostridioides difficile infection in patients with inflammatory bowel disease: Sahil Khanna; Intest Res 2021;19(3):265-274. Published online August 18, 2020; DOI: https://doi.org/10.5217/ir.2020.00045

Abstract PDF PubReader ePub

Inflammatory bowel disease (IBD) is a common diarrheal illness with gastrointestinal and extraintestinal manifestations and complications. The most common infectious complication associated with IBD is Clostridioides difficile infection (CDI). Active IBD predisposes to CDI due to alterations in the gut microbiome. C. difficile is a toxin producing bacterium leading to worsening of underlying IBD, increasing the risk of IBD treatment failure and an increased risk of hospitalization and surgery. Since the symptoms of CDI overlap with those of an IBD flare; it is prudent to recognize that the diagnosis of CDI is challenging and diagnostic tests (nucleic-acid and toxin-based assays) should be interpreted in context of symptoms and test performance. First line treatments for management of CDI in IBD include vancomycin or fidaxomicin. Recurrence prevention strategies should be implemented to mitigate recurrent CDI risk. One needs to monitor IBD disease progression and manage immunosuppression. The risk of recurrent CDI after a primary infection is higher in IBD compared to non-IBD patients. Microbiota restoration therapies are effective to prevent recurrent CDI in IBD patients. This review summarizes the epidemiology, pathophysiology, diagnostic testing, outcomes and management of both CDI and IBD, in CDI complicating IBD.

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David L. Farrier, David Chiang, Amindra S. Arora
Mayo Clinic Proceedings.2024; 99(6): 980. CrossRef
Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system
Linxian Zhao, Tongbo Zhang, Kai Zhang
Frontiers in Immunology.2024;[Epub] CrossRef
Clostridioides difficile infection in inflammatory bowel disease: a clinical review
Mengjun Tang, Chunhua Wang, Ying Xia, Jian Tang, Jiao Wang, Liang Shen
Expert Review of Anti-infective Therapy.2024; 22(5): 297. CrossRef
Management of Clostridioides difficile infection: an Italian Delphi consensus
Matteo Bassetti, Antonio Cascio, Francesco Giuseppe De Rosa, Marianna Meschiari, Roberto Parrella, Nicola Petrosillo, Alessandro Armuzzi, Flavio Caprioli, Francesco Dentali, Marcello Pani, Alberto Pilotto, Umberto Restelli, Maurizio Sanguinetti
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Clinical outcomes for Clostridioides difficile associated diarrhea in inflammatory bowel disease patients versus non-IBD population: A retrospective cohort study
Genady Drozdinsky, Alaa Atamna, Hagar Banai, Haim Ben-Zvi, Jihad Bishara, Noa Eliakim-Raz
Medicine.2023; 102(6): e32812. CrossRef
Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?
Katia Fettucciari, Alessandro Fruganti, Fabrizio Stracci, Andrea Spaterna, Pierfrancesco Marconi, Gabrio Bassotti
International Journal of Molecular Sciences.2023; 24(9): 8155. CrossRef
Low prevalence of Clostridioides difficile infection in acute severe ulcerative colitis: A retrospective cohort study from northern India
Sandeep Mundhra, David Thomas, Saransh Jain, Pabitra Sahu, Sudheer Vuyyuru, Peeyush Kumar, Bhaskar Kante, Rajesh Panwar, Peush Sahni, Rama Chaudhry, Prasenjit Das, Govind Makharia, Saurabh Kedia, Vineet Ahuja
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Oh Chan Kwon, See Young Lee, Jaeyoung Chun, Kyungdo Han, Yuna Kim, Ryul Kim, Min-Chan Park, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park
Frontiers in Medicine.2023;[Epub] CrossRef
Fidaxomicin treatment for Clostridioides difficile infection in patients with inflammatory bowel disease
Andree H Koop, Paul M Travers, Sahil Khanna, Darrell S Pardi, Francis A Farraye, Jana G Hashash
Journal of Gastroenterology and Hepatology.2023; 38(11): 1910. CrossRef
Clostridioides difficile Infection in Inflammatory Bowel Disease Patients: A Systematic Review of Risk Factors and Approach in Management
Leslie Sangurima, Maujid Masood Malik, Nency Ganatra, Rosemary Siby, Sanjay Kumar, Sara Khan, Doju Cheriachan, Lubna Mohammed
Cureus.2023;[Epub] CrossRef
Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B
Katia Fettucciari, Fabrizio Dini, Pierfrancesco Marconi, Gabrio Bassotti
Biology.2023; 12(8): 1117. CrossRef
Gut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field
Elisa Martinez, Sebastien Crevecoeur, Carine Thirion, Jessica Grandjean, Papa Abdoulaye Fall, Marie-Pierre Hayette, Moutschen Michel, Bernard Taminiau, Edouard Louis, Georges Daube
Microorganisms.2023; 11(10): 2527. CrossRef
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Ghassan Abdulrahman Sukkar, Syed Sameer Aga, Abdulrahman Hamid Alsamadani, Faisal Ghazi Almalki, Ali Saleh Alsudais, Abdulrahman Sulaiman Alquzi, Mohamed Eldigire Ahmed, Mushtaq Ahmad Mir, Moudi M. Alasmari, Shivendra Singh
Interdisciplinary Perspectives on Infectious Diseases.2023; 2023: 1. CrossRef
Comparison of 1-Year Colectomy Risk Between the US and Korean Patients with Acute Severe Ulcerative Colitis: A Propensity Score Matching Analysis
Eun Soo Kim, Kyeong Ok Kim, Byung Ik Jang, Eun Young Kim, Yoo Jin Lee, Hyun Seok Lee, Joon Seop Lee, Sung Kook Kim, Yun Jin Jung, Sang-Bum Kang, Manasi Agrawal, Ryan Ungaro, Jean-Frederic Colombel
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Risk factors for Clostridioides difficile infection in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis
Sheng-Bo Fang, Yan-Qing Song, Chun-Yan Zhang, Li-Bo Wang
World Journal of Pediatrics.2022; 18(1): 27. CrossRef
Clostridium innocuum infection in hospitalised patients with inflammatory bowel disease
Puo-Hsien Le, Cheng-Tang Chiu, Pai-Jui Yeh, Yu-Bin Pan, Cheng-Hsun Chiu
Journal of Infection.2022; 84(3): 337. CrossRef
Immunology of Inflammatory Bowel Disease: Molecular Mechanisms and Therapeutics
Quan Lu, Mei-feng Yang, Yu-jie Liang, Jing Xu, Hao-ming Xu, Yu-qiang Nie, Li-sheng Wang, Jun Yao, De-feng Li
Journal of Inflammation Research.2022; Volume 15: 1825. CrossRef
Clostridioides Infection in Patients with Inflammatory Bowel Disease
Mi Rae Lee, Eun Soo Kim
The Korean Journal of Gastroenterology.2022; 80(2): 66. CrossRef
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Seung Hwan Shin, Sang Hyoung Park
The Korean Journal of Gastroenterology.2022; 80(2): 51. CrossRef
Exploration of Potential Gut Microbiota-Derived Biomarkers to Predict the Success of Fecal Microbiota Transplantation in Ulcerative Colitis: A Prospective Cohort in Korea
Gi-Ung Kang, Sowon Park, Yeongyun Jung, Jai J. Jee, Min-Sueng Kim, Seungjun Lee, Dong-Woo Lee, Jae-Ho Shin, Hong Koh
Gut and Liver.2022; 16(5): 775. CrossRef
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Suhyun Park, Sang Hyoung Park
Gut and Liver.2022; 16(5): 663. CrossRef
Microbial Modulation in Inflammatory Bowel Diseases
Jongwook Yu, Jae Hee Cheon
Immune Network.2022;[Epub] CrossRef
Using next-generation sequencing to develop a Shigella species threshold and profile faecal samples from suspected diarrhoea cases
Ann Smith
Folia Microbiologica.2021; 66(3): 399. CrossRef
Decreased secondary faecal bile acids in children with ulcerative colitis and Clostridioides difficile infection
Sarah Rotondo‐Trivette, Beibei Wang, Christopher Gayer, Riddhi Parsana, Yihui Luan, Fengzhu Sun, Sonia Michail
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Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network
Gabrio Bassotti, Alessandro Fruganti, Giovanni Maconi, Pierfrancesco Marconi, Katia Fettucciari
Journal of Inflammation Research.2021; Volume 14: 7443. CrossRef

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IBD

Correlation of serum levels of anti-tumor necrosis factor agents with perianal fistula healing in Crohn’s disease: a narrative review: Eron Fabio Miranda, Rodrigo Bremer Nones, Paulo Gustavo Kotze; Intest Res 2021;19(3):255-264. Published online November 6, 2020; DOI: https://doi.org/10.5217/ir.2020.00029

Abstract PDF PubReader ePub

With the overspread use of measurement of serum levels of anti-tumor necrosis factor (TNF) agents (therapeutic drug monitoring, TDM), new therapeutic strategies have been used in the management of Crohn’s disease (CD). Different targets are correlated with increased levels of circulating drugs. Recent evidence demonstrated that higher serum levels of anti-TNF agents may be associated to better outcomes in perianal fistulizing CD (PFCD). Overall, patients with healed fistulas had higher serum levels of infliximab and adalimumab as compared to those with active drainage. This was demonstrated in some cohort studies, in induction and maintenance, in adults and children with PFCD. In this narrative review, authors summarize current evidence on the use of serum level measurement of anti-TNF agents and its correlation with perianal fistula healing in CD patients. Data on the use of TDM in PFCD is discussed in detail. The retrospective design of the studies and the lack of objective parameters to measure fistula healing are the main limitations of published data. Prospective studies, with central reading of objective radiological parameters, such as pelvic magnetic resonance imaging scores, can improve the level of evidence on the possible advantages of TDM in perianal fistula in CD and are warranted.

Citations

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Management of Perianal Fistulizing Crohn’s Disease
Arshdeep Singh, Vandana Midha, Gursimran Singh Kochhar, Bo Shen, Ajit Sood
Inflammatory Bowel Diseases.2024; 30(9): 1579. CrossRef
Evaluating the Efficacy of Infliximab in Inflammatory Bowel Disease: A Systematic Review of the Literature
Maria P Vallejo, Arturo P Jaramillo, Carlos Luis Guanín Cabrera, Maria G Cueva, Mario Navarro Grijalva, Xavier Grandes
Cureus.2024;[Epub] CrossRef
Comparison of the Pharmacokinetics of CT-P13 Between Crohn’s Disease and Ulcerative Colitis
Eun Soo Kim, Sung Kook Kim, Dong Il Park, Hyo Jong Kim, Yoo Jin Lee, Ja Seol Koo, Eun Sun Kim, Hyuk Yoon, Ji Hyun Lee, Ji Won Kim, Sung Jae Shin, Hyung Wook Kim, Hyun-Soo Kim, Young Sook Park, You Sun Kim, Tae Oh Kim, Jun Lee, Chang Hwan Choi, Dong Soo Ha
Journal of Clinical Gastroenterology.2023; 57(6): 601. CrossRef
Early Infliximab Trough Levels Predict the Long-term Efficacy of Infliximab in a Randomized Controlled Trial in Patients with Active Crohn’s Disease Comparing, between CT-P13 and Originator Infliximab
Jihye Park, Jae Hee Cheon, Kang-Moon Lee, Young-Ho Kim, Byong Duk Ye, Chang Soo Eun, Sung Hyun Kim, Sun Hee Lee, Joon Ho Lee, Stefan Schreiber
Gut and Liver.2023; 17(3): 430. CrossRef
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Mir Zulqarnain, Parakkal Deepak, Andres J. Yarur
Journal of Clinical Medicine.2022; 11(7): 1813. CrossRef
Management of Non-response and Loss of Response to Anti-tumor Necrosis Factor Therapy in Inflammatory Bowel Disease
Jan Marsal, Manuel Barreiro-de Acosta, Irina Blumenstein, Maria Cappello, Thomas Bazin, Shaji Sebastian
Frontiers in Medicine.2022;[Epub] CrossRef
Editorial: higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease
Shana Rakowsky, Adam S. Cheifetz, Konstantinos Papamichael
Alimentary Pharmacology & Therapeutics.2021; 54(8): 1085. CrossRef

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IBD

Anti-inflammatory diet and inflammatory bowel disease: what clinicians and patients should know?: Nor Hamizah Shafiee, Zahara Abdul Manaf, Norfilza M. Mokhtar, Raja Affendi Raja Ali; Intest Res 2021;19(2):171-185. Published online February 3, 2021; DOI: https://doi.org/10.5217/ir.2020.00035

Abstract PDF PubReader ePub

Current treatment for inflammatory bowel disease (IBD) includes the application of anti-inflammatory agents for the induction and remission of IBD. However, prolonged use of anti-inflammatory agents can exert adverse effects on patients. Recently, formulated dietary approach in treating IBD patients is utilized to improve clinical activity scores. An alteration of gastrointestinal microbiota through dietary therapy was found to reduce IBD and is recognized as a promising therapeutic strategy for IBD. One of the recommended formulated diets is an anti-inflammatory diet (AID) that restricts the intake of carbohydrates with modified fatty acids. This diet also contains probiotics and prebiotics that can promote balanced intestinal microbiota composition. However, scientific evidences are limited to support this specific dietary regime in maintaining the remission and prevention relapse of IBD. Therefore, this review aimed to summarize available data from various studies to evaluate the AID diet effectiveness which will be useful for clinicians to manage their IBD patients by application of improved dietary therapy.

Citations

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Diet and Nutrition in Inflammatory Bowel Disease: A Review of the Literature
Scott Manski, Nicholas Noverati, Tatiana Policarpo, Emily Rubin, Raina Shivashankar
Crohn's & Colitis 360.2024;[Epub] CrossRef
Adverse Food Reactions in Inflammatory Bowel Disease: State of the Art and Future Perspectives
Ivan Capobianco, Federica Di Vincenzo, Pierluigi Puca, Guia Becherucci, Maria Chiara Mentella, Valentina Petito, Franco Scaldaferri
Nutrients.2024; 16(3): 351. CrossRef
Nutritional Profile, Disease Severity, and Quality of Life of Patients with Inflammatory Bowel Disease: A Case–Control Study
Lea N. Sayegh, Firas Haddad, Layane Bou Jaoude, Nicole Fakhoury-Sayegh, Gessica N. H. A. Heraoui, Zainab Nasrallah, Charbel Chidiac, Rashad Nawfal, Fadi F. Francis, Fadi H. Mourad, Jana G. Hashash
Nutrients.2024; 16(12): 1826. CrossRef
Dietary Profile of Patients with Inflammatory Bowel Disease in Clinical Remission—A Preliminary Study
Raquel Susana Torrinhas, Ilanna Marques Gomes da Rocha, Danielle Cristina Fonseca, Helena Menezes, Ana Paula Prudêncio, Bianca Depieri Balmant, Letícia Callado, Adérson Omar Mourão Cintra Damião, Natalia Queiroz, Dan L. Waitzberg
Nutrients.2024; 16(14): 2227. CrossRef
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Yue Hou, Sai-Feng Wang, Ke Zhou, Shi-Xue Dai
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Egg white hydrolysate from simulated gastrointestinal digestion alleviates the inflammation and improves the nutritional status in TNBS-induced Crohn’s disease rats
Tianliang Wu, Juanrui Li, Wei Wang, Chenxi Xu, Liying Wang, Long Ding
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Aditi Saha, Isabella Dreyfuss, Humaira Sarfraz, Mark Friedman, Joseph Markowitz
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Lorenzo Bertani, Davide Giuseppe Ribaldone, Massimo Bellini, Maria Gloria Mumolo, Francesco Costa
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Anti-inflammatory properties of Escherichia coli Nissle 1917 in a murine colitis model
Jihye Park, Da Hye Kim, Soochan Kim, Hyun Woo Ma, I Seul Park, Mijeong Son, Ji Hyung Kim, Yoojin Shin, Seung Won Kim, Jae Hee Cheon
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IBD

The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease: Steven Nicolaides, Abhinav Vasudevan, Tony Long, Daniel van Langenberg; Intest Res 2021;19(2):158-170. Published online October 13, 2020; DOI: https://doi.org/10.5217/ir.2020.00008

Abstract PDF PubReader ePub

Smoking significantly increases the risk of developing and worsens Crohn’s disease (CD), yet protects against the development and reduces the severity of ulcerative colitis. It is less clear whether smoking impacts the efficacy of therapeutics in inflammatory bowel disease (IBD). We review the literature regarding the relationship between smoking and the efficacy of medical and surgical therapy in IBD. Smoking is associated with alterations in thiopurine metabolism and may affect time to disease relapse. The outcomes of anti-tumor necrosis factor therapy in active smokers appear neutral with data lacking for newer biologics. Smoking increases the risk of postoperative recurrence in those requiring resection for CD, likely attributable to perturbations of the gut microbiota although further implications of these for disease onset/progression and treatment efficacy remain unclear. Multiple lifestyle and psychosocial confounders are likely under-recognized cofactors in the association between smoking and IBD. Despite the widely promulgated risks associated with cigarette smoking in CD, more incisive data are required to further elucidate the actual relationship between smoking and disease pathways, while accounting for the several negative cofactors prevalent in smokers which cast uncertainty on the magnitude of the direct effect of smoking on disease pathophysiology and the efficacy of therapy.

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Shubha Bhat, Ruishen Lyu, Mitali Agarwal, Michelle Becker, Richard Bloomfeld, David H Bruining, Benjamin L Cohen, Marina Ivanov, Jonathan A Leighton, Alyssa P Stewart, Lindsay Trocke, Stacy S Tse, Ryan C Ungaro, Byron P Vaughn, Miguel Regueiro, Erick Sokn
Inflammatory Bowel Diseases.2024; 30(6): 950. CrossRef
Duration of smoking cessation in patients with inflammatory bowel disease
Carlos González-Muñoza, Cristina Gely, Jordi Gordillo, Federico Bertoletti, Antonio Giordano, Alberto López-Faba, Esther García-Planella
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Alimentary Pharmacology & Therapeutics.2024; 60(5): 604. CrossRef
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Reham Saleh Aljohani, Ali Alaklabi, Yumna Mohammed Alsitary, Majd Abdulrahman bin Khunayn, Shahd Omar Hijazi, Rema Ibraheem Alshagary, Rajkumar Rajendram
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IBD

Endoscopic molecular imaging in inflammatory bowel disease: Nam Seok Ham, Seung-Jae Myung; Intest Res 2021;19(1):33-44. Published online April 20, 2020; DOI: https://doi.org/10.5217/ir.2019.09175

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Molecular imaging is a technique for imaging the processes occurring in a living body at a molecular level in real-time, combining molecular cell biology with advanced imaging technologies using molecular probes and fluorescence. Gastrointestinal endoscopic molecular imaging shows great promise for improving the identification of neoplasms, providing characterization for patient stratification and assessing the response to molecular targeted therapy. In inflammatory bowel disease, endoscopic molecular imaging can be used to assess disease severity and predict therapeutic response and prognosis. Endoscopic molecular imaging is also able to visualize dysplasia in the presence of background inflammation. Several preclinical and clinical trials have evaluated endoscopic molecular imaging; however, this area is just beginning to evolve, and many issues have not been solved yet. In the future, it is expected that endoscopic molecular imaging will be of increasing interest among clinicians as a new technology for the identification and evaluation of colorectal neoplasm and colitis-associated cancer.

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Intestinal tuberculosis or Crohn’s disease: a review of the diagnostic models designed to differentiate between these two gastrointestinal diseases: Julajak Limsrivilai, Nonthalee Pausawasdi; Intest Res 2021;19(1):21-32. Published online April 22, 2020; DOI: https://doi.org/10.5217/ir.2019.09142

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Differentiating Crohn’s disease (CD) from intestinal tuberculosis (ITB) is a diagnostic dilemma, particularly in regions where ITB is prevalent and CD incidence is increasing, because both diseases can present quite similarly, and diagnostic tests to identify Mycobacterium tuberculosis in tissue samples have rather poor sensitivity. Studies that were conducted to determine the factors that differentiate CD from ITB identified some significant characteristics, but none of those characteristics are exclusive to either ITB or CD. Many diagnostic models or scoring systems that use one to several diagnostic parameters have been proposed to help distinguish these two intestinal diseases. Early models consisted of parameters common to routine clinical practice, such as clinical features, and endoscopic and pathologic findings. The later models also include more advanced diagnostic parameters like high-resolution imaging and serological testing. However, the number and types of parameters differ among diagnostic models, and the systems used to calculate scoring also vary from model to model. Enhanced awareness and understanding of the currently available diagnostic models will help physicians determine which model(s) is/are most suitable for differentiating CD from ITB in their clinical practice.

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Intestinal Research.2022; 20(4): 418. CrossRef
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Cancer

Two intertwined compartments coexisting in sporadic conventional colon adenomas: Carlos A. Rubio; Intest Res 2021;19(1):12-20. Published online February 24, 2020; DOI: https://doi.org/10.5217/ir.2019.00133

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Sporadic conventional colon adenomas are microscopically built of 2 intertwined compartments: one on top, harboring the dysplastic tissue that defines their histo-biomolecular attributes, and the other below, composed of non-dysplastic crypts with corrupted shapes (CCS). The CCS of 306 colon adenomas revealed asymmetric, haphazardly-distributed proliferating cell-domains (PC). In contrast, the PC-domains in normal controls were symmetric, being limited to the lower thirds of the crypts. In 28% out of 501 sporadic conventional adenomas, foci of p53-upregulated dysplastic tissue were found. The CCS in 30% of 108 sporadic adenomas showed p53-upregulated single cells, suggesting mounting somatic mutations. No p53-upregulated cells were found in the crypts of controls. In polypoid adenomas, the mucosa of the stalk without dysplastic tissue on top disclosed CCS with asymmetrical PC-domains and single p53-upregulated cells. The latter observations suggested that CCS had developed prior to and not after the growth of the dysplastic tissue on top. CCS were also found below colon adenomas in carcinogen-treated rats. It is concluded that the 2 intertwined histo-biological compartments of sporadic conventional colon adenomas are probably interdependent components. These findings may open new directions aimed to uncover the link between the normal colonic mucosa and the histogenesis of, conventional adenomas.

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Calcium, Vitamin D, and Colorectal Cancer
Young-Jo Wi, Soo-Young Na
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Yoon Suk Jung
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Asymmetric crypt fission in colectomy specimens in patients with ulcerative colitis
Carlos A Rubio, Peter T Schmidt
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141 Download
5 Web of Science
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IBD

Pouchitis in inflammatory bowel disease: a review of diagnosis, prognosis, and treatment: Shintaro Akiyama, Victoria Rai, David T. Rubin; Intest Res 2021;19(1):1-11. Published online November 5, 2020; DOI: https://doi.org/10.5217/ir.2020.00047

Abstract PDF PubReader ePub

Patients with inflammatory bowel disease (IBD) occasionally need a restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) because of medically refractory colitis or dysplasia/cancer. However, pouchitis may develop in up to 70% of patients after this procedure and significantly impair quality of life, more so if the inflammation becomes a chronic condition. About 10% of patients with IBD who develop pouchitis require pouch excision, and several risk factors of the failure have been reported. A phenotype that has features similar to Crohn’s disease may develop in a subset of ulcerative colitis patients following proctocolectomy with IPAA and is the most frequent reason for pouch failure. In this review, we discuss the diagnosis and prognosis of pouchitis, risk factors for pouchitis development, and treatment options for pouchitis, including the newer biological agents.

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Davide Giuseppe Ribaldone, Giulia Testa, Bram Verstockt, Tamas Molnar, Edoardo Savarino, Carsten Schmidt, Sophie Vieujean, Niels Teich, Corina Meianu, Pascal Juillerat, Nathan Grellier, Triana Lobaton
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Association of colonic metaplasia of goblet cells and endoscopic phenotypes of the J pouch in patients with ulcerative colitis: a retrospective pilot study
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Intestinal Research.2024; 22(1): 92. CrossRef
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Alex L. Huang, Marnie Abeshouse, Katherine C. Lee, Emily Rinebold, Maia Kayal, Michael C. Plietz
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Treatment of Chronic Pouchitis With JAK Inhibitors: Results from A Large Multicenter Database
Saqr Alsakarneh, Aakash Desai, Gursimran S Kochhar, Francis A Farraye, Jana G Hashash
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Corina Meianu, Tudor Stroie, Doina Istratescu, Carmen Monica Preda, Mihai Mircea Diculescu
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Rodrigo Castaño Llano, Sandra Patricia Molina Meneses, Juan Darío Puerta, René Marcelo Escobar, Santiago Salazar Ochoa, Juan Esteban Puerta, Manuel Barreiro-de Acosta
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Aline C. Fenneman, Melissa Weidner, Lea Ann Chen, Max Nieuwdorp, Martin J. Blaser
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Inflammatory bowel diseases

Fibrostenotic strictures in Crohn’s disease: Jun Hwan Yoo, Stefan Holubar, Florian Rieder; Intest Res 2020;18(4):379-401. Published online April 10, 2020; DOI: https://doi.org/10.5217/ir.2019.09148

Abstract PDF PubReader ePub

The use of biologic agents including anti-tumor necrosis factor monoclonal antibodies followed by anti-integrins and anti-interleukins has drastically changed the treatment paradigm of Crohn’s disease (CD) by improving clinical symptoms and mucosal healing. However, up to 70% of CD patients still eventually undergo surgery mainly due to fibrostenotic strictures. There are no specific anti-fibrotic drugs yet. This review comprehensively addresses the mechanism, prediction, diagnosis and treatment of the fibrostenotic strictures in CD. We also introduce promising anti-fibrotic agents which may be available in the near future and summarize challenges in developing novel therapies to treat fibrostenotic strictures in CD.

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Inflammatory bowel diseases

Colitis and Crohn’s Foundation (India) consensus statements on use of 5-aminosalicylic acid in inflammatory bowel disease: Ajit Sood, Vineet Ahuja, Vandana Midha, Saroj Kant Sinha, C. Ganesh Pai, Saurabh Kedia, Varun Mehta, Sawan Bopanna, Philip Abraham, Rupa Banerjee, Shobna Bhatia, Karmabir Chakravartty, Sunil Dadhich, Devendra Desai, Manisha Dwivedi, Bhabhadev Goswami, Kirandeep Kaur, Rajeev Khosla, Ajay Kumar, Ramit Mahajan, S. P. Misra, Kiran Peddi, Shivaram Prasad Singh, Arshdeep Singh; Intest Res 2020;18(4):355-378. Published online July 13, 2020; DOI: https://doi.org/10.5217/ir.2019.09176

Abstract PDF PubReader ePub

Despite several recent advances in therapy in inflammatory bowel disease (IBD), 5-aminosalicylic acid (5-ASA) therapy has retained its place especially in ulcerative colitis. This consensus on 5-ASA is obtained through a modified Delphi process, and includes guiding statements and recommendations based on literature evidence (randomized trials, and observational studies), clinical practice, and expert opinion on use of 5-ASA in IBD by Indian gastroenterologists. The aim is to aid practitioners in selecting appropriate treatment strategies and facilitate optimal use of 5-ASA in patients with IBD.

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The impact of 5-aminosalicylates on the efficacy of mesenchymal stem cell therapy in a murine model of ulcerative colitis
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The impact of clinical experience on decision-making regarding the treatment and management of mild-to-moderate ulcerative colitis
Jae Hee Cheon, Kristine Paridaens, Sameer Al Awadhi, Jakob Begun, John R Fullarton, Edouard Louis, Fernando Magro, Juan Ricardo Marquez, Alexander R Moschen, Neeraj Narula, Grazyna Rydzewska, Axel U Dignass, Simon PL Travis
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Development of Novel pH-Sensitive Eudragit Coated Beads Containing Curcumin-Mesalamine Combination for Colon-Specific Drug Delivery
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Inflammatory bowel diseases

Clinical management for small bowel of Crohn’s disease in the treat-to-target era: now is the time to optimize treatment based on the dominant lesion: Kenji Watanabe; Intest Res 2020;18(4):347-354. Published online October 26, 2020; DOI: https://doi.org/10.5217/ir.2020.00032

Abstract PDF PubReader ePub

A treat-to-target strategy, in which treatment is continuously adjusted according to the results of scheduled objective monitoring, is optimal for patients with Crohn’s disease (CD) in the era of biologics. The small bowel is a common site of intractable CD, which may result from multiple strictures or expanding lesions. To improve the prognosis of patients with small bowel CD, lesions should be proactively monitored within the subclinical phase. Objective assessment of small bowel lesions is technically difficult, however, due to the relatively poor correlation between endoscopic activity and clinical symptoms or biomarker titers. The presence of proximal small bowel lesions and asymptomatic “Real Silent CD” must be considered. Endoscopy remains the gold standard to assess these lesions. In clinical practice, the advantages and disadvantages of each imaging modality and biomarker must be carefully weighed for appropriate application and reliable monitoring. The prevalence of small bowel lesions depends on the precision of the imaging modality used for detection. Clinical management should be based on the dominant location of the intestinal lesions rather than classical classification. Optimal strategies for detecting and treating small bowel lesions in patients with CD must be developed utilizing reliable, precise, and objective monitoring.

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NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease: Katsuyoshi Matsuoka; Intest Res 2020;18(3):275-281. Published online June 3, 2020; DOI: https://doi.org/10.5217/ir.2020.00002

Abstract PDF PubReader ePub

Thiopurine has been used to maintain remission and to reduce antidrug antibody formation in monoclonal antibody therapy in patients with inflammatory bowel disease (IBD). The use of thiopurine is limited by side effects such as leukopenia. Thiopurine S-methyltransferase (TPMT) variants are associated with thiopurine-induced leukopenia in Westerners, but the frequency of the risk alleles is low in Asians. Recently, a variant in the nudix hydrolase 15 (NUDT15) gene (R139C, c.415C > T) was reported to be associated with early severe leukopenia in Asians. NUDT15 is an enzyme that converts 6-thio-(deoxy)guanosine triphosphate (6-T(d)GTP) to 6-thio-(deoxy)guanosine monophosphate (6-T(d)GMTP). The R139C variant impairs the stability of the protein and increases incorporation of 6-TGTP and 6-TdGTP into RNA and DNA, respectively, resulting in leukopenia. The frequency of C/C, C/T, and T/T are approximately 80%, 20%, and 1%, respectively in East Asians. Early leukopenia occurred in less than 3% of patients with C/C and in around 20% of those with C/T, whereas it occurred in almost all patients with T/T. Patients homozygous for this variant also develop severe hair loss. The measurement of NUDT15 R139C can increase the safety of thiopurine dramatically and is a successful example of personalized medicine in the field of IBD.

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310 Download
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Inflammatory bowel diseases

Capsule endoscopy in inflammatory bowel disease: when and how: Ida Hilmi, Taku Kobayashi; Intest Res 2020;18(3):265-274. Published online July 7, 2020; DOI: https://doi.org/10.5217/ir.2019.09165

Abstract PDF PubReader ePub

Capsule endoscopy (CE) is emerging as an important investigation in inflammatory bowel disease (IBD); common types include the standard small bowel CE and colon CE. More recently, the pan-enteric CE was developed to assess the large and small bowel in patients with Crohn’s disease (CD). Emerging indications include noninvasive assessment for mucosal healing (both in the small bowel and the colon) and detection of postoperative recurrence in patients with CD. Given the increasing adoption, several CE scoring systems have been specifically developed for IBD. The greatest concern with performing CE, particularly in CD, is capsule retention, but this can be overcome by performing cross-sectional imaging such as magnetic resonance enterography and using patency capsules before performing the procedure. The development of software for automated detection of mucosal abnormalities typically seen in IBD may further increase its adoption.

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Frontline Gastroenterology.2024; 15(4): 273. CrossRef
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Jihye Park, Jin Su Kim, Joo Hye Song, Kwangwoo Nam, Seong-Eun Kim, Eui Sun Jeong, Jae Hyun Kim, Seong Ran Jeon
Gut and Liver.2024; 18(4): 686. CrossRef
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The Korean Journal of Internal Medicine.2022; 37(3): 567. CrossRef
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Diagnostics.2022; 12(4): 954. CrossRef
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Frontiers in Pharmacology.2022;[Epub] CrossRef
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Inflammatory bowel diseases

Pathogenesis and clinical perspectives of extraintestinal manifestations in inflammatory bowel diseases: Jung Min Kim, Jae Hee Cheon; Intest Res 2020;18(3):249-264. Published online April 18, 2020; DOI: https://doi.org/10.5217/ir.2019.00128

Abstract PDF PubReader ePub

A considerable number of patients with inflammatory bowel disease (IBD) experience extraintestinal manifestations (EIMs), which can present either before or after IBD diagnosis. Unraveling the pathogenic pathways of EIMs in IBD is challenging because of the lack of reliable criteria for diagnosis and difficulty in distinguishing EIMs from external pathologies caused by drugs or other etiologies. Optimizing treatment can also be difficult. Early diagnosis and management of EIM revolve around multidisciplinary teams, and they should have the resources necessary to make and implement appropriate decisions. In addition, specialists of the affected organs should be trained in IBD treatment. Furthermore, patient awareness regarding the extraintestinal symptoms of IBD is of paramount importance for improving patient understanding of disease and health outcomes. Herein, we review the pathogenesis and clinical perspectives of EIMs in IBD.

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The Journal of Nutritional Biochemistry.2022; 99: 108855. CrossRef
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Gut and Liver.2022; 16(4): 555. CrossRef
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The Ewha Medical Journal.2022; 45(2): 35. CrossRef
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Journal of Clinical Medicine.2021; 10(24): 5984. CrossRef

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Novel biomarkers for the diagnosis and prognosis of colorectal cancer: Hyung-Hoon Oh, Young-Eun Joo; Intest Res 2020;18(2):168-183. Published online November 30, 2019; DOI: https://doi.org/10.5217/ir.2019.00080

Abstract PDF PubReader ePub

Colorectal cancer (CRC) is among the most common malignancies and remains a major cause of cancer-related death worldwide. Despite recent advances in surgical and multimodal therapies, the overall survival of advanced CRC patients remains very low. Cancer progression, including invasion and metastasis, is a major cause of death among CRC patients. The underlying mechanisms of action resulting in cancer progression are beginning to unravel. The reported molecular and biochemical mechanisms that might contribute to the phenotypic changes in favor of carcinogenesis include apoptosis inhibition, enhanced tumor cell proliferation, increased invasiveness, cell adhesion perturbations, angiogenesis promotion, and immune surveillance inhibition. These events may contribute to the development and progression of cancer. A biomarker is a molecule that can be detected in tissue, blood, or stool samples to allow the identification of pathological conditions such as cancer. Thus, it would be beneficial to identify reliable and practical molecular biomarkers that aid in the diagnostic and therapeutic processes of CRC. Recent research has targeted the development of biomarkers that aid in the early diagnosis and prognostic stratification of CRC. Despite that, the identification of diagnostic, prognostic, and/or predictive biomarkers remains challenging, and previously identified biomarkers might be insufficient to be clinically applicable or offer high patient acceptability. Here, we discuss recent advances in the development of molecular biomarkers for their potential usefulness in early and less-invasive diagnosis, treatment, and follow-up of CRC.

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Cancer Science.2024; 115(3): 734. CrossRef
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Cancer Biomarkers.2024; 40(1): 95. CrossRef
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Shan Li, Ting Li, Yan-Qing Shi, Bin-Jie Xu, Yu-Yong Deng, Xu-Guang Sun
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International Immunopharmacology.2024; 133: 112125. CrossRef
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Current Cancer Drug Targets.2024; 24(6): 595. CrossRef
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Danique J. I. Heuvelings, Anne G. W. E. Wintjens, Laura Moonen, Sanne M. E. Engelen, Ignace H. J. T. de Hingh, Liselot B. Valkenburg-van Iersel, Marcel den Dulk, Jan Beckervordersandforth, Sharon G. M. Thijssen, Daphne J. G. Leunissen, Laurents P. S. Stas
International Journal of Molecular Sciences.2023; 24(16): 12830. CrossRef
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Iqbal Jalaludin, David M. Lubman, Jeongkwon Kim
Mass Spectrometry Reviews.2023; 42(2): 844. CrossRef
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The Korean Journal of Internal Medicine.2023; 38(2): 264. CrossRef
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Yifei Chen, Lizhen Ye, Hui Chen, Tingting Fan, Cheng Qiu, Yan Chen, Yuyang Jiang
Biosensors.2023; 13(1): 78. CrossRef
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Cancers.2023; 15(2): 549. CrossRef
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Xiao Meng Pei, Heong Ting Wong, Simon Siu Man Ng, Wing Wa Leung, Yee Ni Wong, Hin Fung Tsang, Amanda Kit Ching Chan, Yin Kwan Evelyn Wong, Allen Chi Shing Yu, Aldrin Kay Yuen Yim, William Chi Shing Cho, John Kwok Cheung Chan, Kwong Fai Wong, John M Luk, W
Expert Review of Molecular Diagnostics.2023; 23(2): 171. CrossRef
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Song Guo, Bingtan Song, Lin Li, Hesheng Li, Tao Yang, Lianmeng Cao, Jian Wang, Fu Wang
Journal of Immunology Research.2023; 2023: 1. CrossRef
Ferroptosis open a new door for colorectal cancer treatment
Hong Liang, Xia He, Yitong Tong, Niuniu Bai, Yushu Pu, Ke Han, Yi Wang
Frontiers in Oncology.2023;[Epub] CrossRef
Novel biomarkers used for early diagnosis and tyrosine kinase inhibitors as targeted therapies in colorectal cancer
Huafeng Jiang, Senjun Zhou, Gang Li
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Inflammatory bowel diseases

Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models: Emiko Mizoguchi, Daren Low, Yui Ezaki, Toshiyuki Okada; Intest Res 2020;18(2):151-167. Published online April 20, 2020; DOI: https://doi.org/10.5217/ir.2019.09154

Abstract PDF PubReader ePub

The specific pathogenesis underlining inflammatory bowel disease (IBD) is very complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major forms of IBD, Crohn’s disease (CD) and ulcerative colitis (UC), and both disorders affect individuals throughout life. Despite every extensive effort, the interplay among genetic factors, immunological factors, environmental factors and intestinal microbes is still completely unrevealed. Animal models are indispensable to find out mechanistic details that will facilitate better preclinical setting to target specific components involved in the pathogenesis of IBD. Based on many recent reports, dysbiosis of the commensal microbiota is implicated in the pathogenesis of several diseases, not only IBD but also colon cancer, obesity, psoriasis as well as allergic disorders, in both human and animal models. Advanced technologies including cell-specific and inducible knockout systems, which are recently employed to mouse IBD models, have further enhanced the ability of developing new therapeutic strategies for IBD. Furthermore, data from these mouse models highlight the critical involvement of dysregulated immune responses and impaired colonic epithelial defense system in the pathogenesis of IBD. In this review, we will explain from the history of animal models of IBD to the recent reports of the latest compounds, therapeutic strategies, and approaches tested on IBD animal models.

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Seminars in Arthritis and Rheumatism.2024; 65: 152362. CrossRef
Unveiling Colitis: A Journey through the Dextran Sodium Sulfate-induced Model
Chunhua Yang, Didier Merlin
Inflammatory Bowel Diseases.2024; 30(5): 844. CrossRef
An evaluation of animal models for using bioactive compounds in the treatment of inflammatory bowel disease
Shanshan Tie, Yannan Chen, Mingqian Tan
Food Frontiers.2024; 5(2): 474. CrossRef
Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products
Tenzin Jamtsho, Karma Yeshi, Matthew J. Perry, Alex Loukas, Phurpa Wangchuk
Pharmaceuticals.2024; 17(3): 283. CrossRef
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Natticha Sumneang, Komsak Pintha, Sarawut Kongkarnka, Maitree Suttajit, Napapan Kangwan
Molecules.2024; 29(9): 1940. CrossRef
Sacroiliitis in inflammatory bowel disease on abdominal computed tomography: prevalence, misses, and associated factors
DK Kim, K-C Lee, JK Kim
Scandinavian Journal of Rheumatology.2024; 53(4): 248. CrossRef
Dopamine β-hydroxylase shapes intestinal inflammation through modulating T cell activation
Qiaoling Sun, Heng Li, Jing Lv, Weilin Shi, Yanfeng Bai, Ke Pan, Alice Chen
Cellular Immunology.2024; 401-402: 104839. CrossRef
Cellular succinate metabolism and signaling in inflammation: implications for therapeutic intervention
Hong Huang, Gejing Li, Yini He, Jing Chen, Jianye Yan, Qin Zhang, Liqing Li, Xiong Cai
Frontiers in Immunology.2024;[Epub] CrossRef
Advances in Vascular Diagnostics using Magnetic Particle Imaging (MPI) for Blood Circulation Assessment
Marisa O Pacheco, Isabelle K Gerzenshtein, Whitney L Stoppel, Carlos M Rinaldi‐Ramos
Advanced Healthcare Materials.2024;[Epub] CrossRef
Modelling the innate immune system in microphysiological systems
Michael J. Rupar, Hannah Hanson, Stephanie Rogers, Brianna Botlick, Steven Trimmer, James J. Hickman
Lab on a Chip.2024; 24(15): 3604. CrossRef
DAMP-ing IBD: Extinguish the Fire and Prevent Smoldering
Oliver Sandys, Pieter C. F. Stokkers, Anje A. te Velde
Digestive Diseases and Sciences.2024;[Epub] CrossRef
Bioinspired and bioderived nanomedicine for inflammatory bowel disease
Rafaela Gazzi, Rita Gelli, Simone Aleandri, Marianna Carone, Paola Luciani
WIREs Nanomedicine and Nanobiotechnology.2024;[Epub] CrossRef
MiRNA-Based Therapies for the Treatment of Inflammatory Bowel Disease: What Are We Still Missing?
Tommaso Innocenti, Elisabetta Bigagli, Erica Nicola Lynch, Andrea Galli, Gabriele Dragoni
Inflammatory Bowel Diseases.2023; 29(2): 308. CrossRef
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation
Hoyul Lee, Jae Han Jeon, Yu-Jeong Lee, Mi-Jin Kim, Woong Hee Kwon, Dipanjan Chanda, Themis Thoudam, Haushabhau S. Pagire, Suvarna H. Pagire, Jin Hee Ahn, Robert A. Harris, Eun Soo Kim, In-Kyu Lee
Cellular and Molecular Gastroenterology and Hepatology.2023; 15(2): 439. CrossRef
Korean clinical practice guidelines on biologics for moderate to severe Crohn’s disease
Seong-Joon Koh, Sung Noh Hong, Soo-Kyung Park, Byong Duk Ye, Kyeong Ok Kim, Jeong Eun Shin, Yong Sik Yoon, Hong Sub Lee, Sung Hoon Jung, Miyoung Choi, Soo-Young Na, Chang Hwan Choi, Joo Sung Kim
Intestinal Research.2023; 21(1): 43. CrossRef
Potential of Gut Microbe-Derived Extracellular Vesicles to Differentiate Inflammatory Bowel Disease Patients from Healthy Controls
Min Heo, Young Soo Park, Hyuk Yoon, Nam-Eun Kim, Kangjin Kim, Cheol Min Shin, Nayoung Kim, Dong Ho Lee
Gut and Liver.2023; 17(1): 108. CrossRef
Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review
Jung Yoon Jang, Eunok Im, Nam Deuk Kim
International Journal of Molecular Sciences.2023; 24(3): 1954. CrossRef
Factors associated with the prescription of probiotics in patients with inflammatory bowel disease: a cross-sectional study
Joo Kyung Kim, Jae Hee Cheon
Journal of Yeungnam Medical Science.2023; 40(1): 37. CrossRef
Compositional changes in fecal microbiota associated with clinical phenotypes and prognosis in Korean patients with inflammatory bowel disease
Seung Yong Shin, Young Kim, Won-Seok Kim, Jung Min Moon, Kang-Moon Lee, Sung-Ae Jung, Hyesook Park, Eun Young Huh, Byung Chang Kim, Soo Chan Lee, Chang Hwan Choi
Intestinal Research.2023; 21(1): 148. CrossRef
miRNA Molecules—Late Breaking Treatment for Inflammatory Bowel Diseases?
Ioanna Aggeletopoulou, Athanasia Mouzaki, Konstantinos Thomopoulos, Christos Triantos
International Journal of Molecular Sciences.2023; 24(3): 2233. CrossRef
Succinate metabolism and its regulation of host-microbe interactions
Yi-han Wei, Xi Ma, Jiang-chao Zhao, Xiu-qi Wang, Chun-qi Gao
Gut Microbes.2023;[Epub] CrossRef
A westernized diet changed the colonic bacterial composition and metabolite concentration in a dextran sulfate sodium pig model for ulcerative colitis
Farhad M. Panah, Katrine D. Nielsen, Gavin L. Simpson, Anna Schönherz, Andreas Schramm, Charlotte Lauridsen, Tina S. Nielsen, Ole Højberg, Marlene Fredborg, Stig Purup, Nuria Canibe
Frontiers in Microbiology.2023;[Epub] CrossRef
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Journal of Pharmacology and Experimental Therapeutics.2023; 386(1): 35. CrossRef
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Yu Kyung Jun, Da-Ae Yu, Yoo Min Han, Soo Ran Lee, Seong-Joon Koh, Hyunsun Park
Dermatology and Therapy.2023; 13(7): 1465. CrossRef
Probiotics for the treatment of ulcerative colitis: a review of experimental research from 2018 to 2022
Cuilan Huang, Wujuan Hao, Xuyang Wang, Renmin Zhou, Qiong Lin
Frontiers in Microbiology.2023;[Epub] CrossRef
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Journal of Medicinal Chemistry.2023; 66(15): 10473. CrossRef
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Jae-Young Lee, Hyun Woo Ma, Ji Hyung Kim, I Seul Park, Mijeong Son, Keun Ho Ryu, Jieun Shin, Seung Won Kim, Jae Hee Cheon
Gut and Liver.2023; 17(5): 766. CrossRef
Regional variations in the prevalence of primary sclerosing cholangitis associated with inflammatory bowel disease
Kwang Woo Kim, Hyoun Woo Kang
Intestinal Research.2023; 21(4): 413. CrossRef
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Seung Won Kim, Jae-Young Lee, Han Cheol Lee, Jae Bum Ahn, Ji Hyung Kim, I Seul Park, Jae Hee Cheon, Duk Hwan Kim
Gut and Liver.2023; 17(6): 905. CrossRef
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International Journal of Molecular Sciences.2023; 24(24): 17484. CrossRef
Animal models of inflammatory bowel disease: category and evaluation indexes
Changlin Wen, Dan Chen, Rao Zhong, Xi Peng
Gastroenterology Report.2023;[Epub] CrossRef
Recent development in zebrafish model for bioactivity and safety evaluation of natural products
Fang-Jun Lin, Hang Li, Ding-Tao Wu, Qi-Guo Zhuang, Hua-Bin Li, Fang Geng, Ren-You Gan
Critical Reviews in Food Science and Nutrition.2022; 62(31): 8646. CrossRef
Potential benefits of immunomodulator use with vedolizumab for maintenance of remission in ulcerative colitis
Makoto Naganuma, Kenji Watanabe, Satoshi Motoya, Haruhiko Ogata, Toshiyuki Matsui, Yasuo Suzuki, Lyann Ursos, Shigeru Sakamoto, Mitsuhiro Shikamura, Tetsuharu Hori, Jovelle Fernandez, Mamoru Watanabe, Toshifumi Hibi, Takanori Kanai
Journal of Gastroenterology and Hepatology.2022; 37(1): 81. CrossRef
Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower, Kathleen A. Farley, Margaret Fleming, Andrew Flick, Richard K. Frisbie, Justin Hall, David Hepworth, Hannah Jones, John D. Knafels, Steve Kortum, Frank E. Lovering, Jo
Journal of Medicinal Chemistry.2022; 65(1): 757. CrossRef
Copper oxide nanoparticles synthesized from Trichosanthes kirilowii ameliorates the DSS-induced acute colitis in mice through the suppression of inflammatory responses
Xuefeng Jiang, Yu Sun, Tahani Awad Alahmadi, Velu Manikandan, Thamaraiselvan Rengarajan, Yuyang Zhao
Journal of King Saud University - Science.2022; 34(3): 101817. CrossRef
Screening and Evaluation of Probiotics for Reducing Intestinal Inflammation
雅君陈
Hans Journal of Food and Nutrition Science.2022; 11(01): 44. CrossRef
Jianpi Qingchang Decoction Ameliorates Chronic Colitis in Piroxicam-Induced IL-10 Knockout Mice by Inhibiting Endoplasmic Reticulum Stress
Qian Chen, Ya-Li Zhang, Zi-Wei Zhang, Yu-Jun Chen, Ying-Jue Tang, Dan Qiao, Yan-Cheng Dai, Zhi-Peng Tang, Lu sa Mota da Silva
Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1. CrossRef
Reactive Oxygen Species-Responsive Polyether Micelle Nanomaterials for Targeted Treatment of Ulcerative Colitis
Xin-Xin Zhao, Shan-Bo Ma, Jin-Peng Wen, Da-Tao Hu, Ju-Shan Gao, Qiao Peng, Yu-Chen Zhang, Jin-Qing Wang, Ke Wang, Xiao-Peng Shi
Journal of Biomedical Nanotechnology.2022; 18(1): 120. CrossRef
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Olga Hartwig, Brigitta Loretz, Adrien Nougarede, Dorothée Jary, Eric Sulpice, Xavier Gidrol, Fabrice Navarro, Claus-Michael Lehr
Journal of Controlled Release.2022; 345: 646. CrossRef
Asymptomatic sacroiliitis detected by magnetic resonance enterography in patients with Crohn's disease: prevalence, association with clinical data, and reliability among radiologists in a multicenter study of adult and pediatric population
Lorenzo Cereser, Giovanni Zancan, Ivan Giovannini, Carmelo Cicciò, Ilaria Tinazzi, Angela Variola, Matteo Bramuzzo, Flora Maria Murru, Marco Marino, Annarita Tullio, Salvatore De Vita, Rossano Girometti, Alen Zabotti
Clinical Rheumatology.2022; 41(8): 2499. CrossRef
Update on the epidemiology of inflammatory bowel disease in Asia: where are we now?
Sang Hyoung Park
Intestinal Research.2022; 20(2): 159. CrossRef
Polysaccharides from soybean residue fermented by Neurospora crassa alleviate DSS-induced gut barrier damage and microbiota disturbance in mice
Wenli Huang, Zeyuan Deng, Ling Lu, Yaoming Ouyang, Shuyuan Zhong, Ting Luo, Yawei Fan, Liufeng Zheng
Food & Function.2022; 13(10): 5739. CrossRef
Mesenchymal stem cell treatment for enteric neuropathy in the Winnie mouse model of spontaneous chronic colitis
Ainsley M. Robinson, Rhian Stavely, Sarah Miller, Rajaraman Eri, Kulmira Nurgali
Cell and Tissue Research.2022; 389(1): 41. CrossRef
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Differentiation of fibrotic and inflammatory component of Crohn’s disease-associated strictures: Jordi Rimola, Nunzia Capozzi; Intest Res 2020;18(2):144-150. Published online April 20, 2020; DOI: https://doi.org/10.5217/ir.2020.00015

Abstract PDF PubReader ePub

Patients with Crohn’s disease (CD) commonly develop bowel strictures, which may contain various degrees of inflammation and fibrosis. While predominantly inflammatory strictures may benefit from a medical anti-inflammatory treatment approach, fibrotic strictures would require endoscopic balloon dilation or surgery. Cross-sectional imaging surpasses endoscopy for characterization of stenotic segments and potentially may contribute to the optimal clinical management of these patients. This short review aims to discuss the potentialities and limitations of cross-sectional imaging techniques for assessing bowel fibrosis in patients with CD.

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Inflammation Research.2024; 73(8): 1359. CrossRef
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Alex L. Huang, Marnie Abeshouse, Katherine C. Lee, Emily Rinebold, Maia Kayal, Michael C. Plietz
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Cellular and Molecular Gastroenterology and Hepatology.2023; 15(4): 1000. CrossRef
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Anuj Bohra, Abhinav Vasudevan, Numan Kutaiba, Daniel Ross Van Langenberg
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Journal of Clinical Medicine.2023; 12(9): 3052. CrossRef
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Zeitschrift für Gastroenterologie.2022; 60(06): 978. CrossRef
Crohn's disease related strictures in cross‐sectional imaging: More than meets the eye?
Joseph Sleiman, Prathyush Chirra, Namita S. Gandhi, Mark E. Baker, Cathy Lu, Ilyssa O. Gordon, Satish E. Viswanath, Florian Rieder
United European Gastroenterology Journal.2022; 10(10): 1167. CrossRef
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Joseph Sleiman, Sara El Ouali, Taha Qazi, Benjamin Cohen, Scott R. Steele, Mark E. Baker, Florian Rieder
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Biosimilars: concept, current status, and future perspectives in inflammatory bowel diseases: Sang Hyoung Park, Jae Cheol Park, Milan Lukas, Martin Kolar, Edward V. Loftus, Jr; Intest Res 2020;18(1):34-44. Published online January 30, 2020; DOI: https://doi.org/10.5217/ir.2019.09147

Abstract PDF PubReader ePub

The inflammatory bowel diseases (IBD), which consist of Crohn’s disease and ulcerative colitis, are chronic, incurable immunemediated inflammatory disorders of the intestine. As IBD incidence continues to increase globally and its mortality is low, prevalent cases of IBD are rapidly increasing, thereby leading to a substantial increase in health care costs. Although the introduction of biologic agents for IBD management has revolutionized the armamentarium of IBD therapy, the high cost of this therapy is concerning. With the expirations of patents for existing biologic agents (originals), biosimilars with cheaper costs have been highlighted in the field of IBD. Despite concerns regarding their short- and long-term efficacy, safety, immunogenicity, and interchangeability, increasing evidence via prospective observations and phase III or IV clinical trials, which aim to prove the “biosimilarity” of biosimilars to originals, has partly confirmed their efficacy, safety, and interchangeability. Additionally, although patients and physicians are reluctant to use biosimilars, a positive budget impact has been reported owing to their use in different countries. In the near future, multiple biosimilars with lower costs, and efficacy and safety profile similar to originals, could be used to treat IBD; thus, further consideration and knowledge dissemination are warranted in this new era of biosimilars.

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Journal of Clinical Gastroenterology.2023; 57(6): 601. CrossRef
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Gut and Liver.2023; 17(3): 430. CrossRef
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Quentin Jarrion, Brahim Azzouz, James Robinson, Damien Jolly, Catherine Vallet, Thierry Trenque
Therapies.2022; 77(4): 467. CrossRef
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Frontiers in Medicine.2022;[Epub] CrossRef
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Journal of Clinical Medicine.2021; 10(22): 5311. CrossRef

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Inflammatory bowel diseases

Prevention and management of viral hepatitis in inflammatory bowel disease: a clinical practice guideline by the Korean Association for the Study of Intestinal Diseases: Soo-Kyung Park, Chang Hwan Choi, Jaeyoung Chun, Heeyoung Lee, Eun Sun Kim, Jae Jun Park, Chan Hyuk Park, Bo-In Lee, Yunho Jung, Dong-Il Park, Do Young Kim, Hana Park, Yoon Tae Jeen, IBD Research Group of the Korean Association for the Study of Intestinal Diseases; Intest Res 2020;18(1):18-33. Published online January 30, 2020; DOI: https://doi.org/10.5217/ir.2019.09155

Abstract PDF PubReader ePub

The treatment of inflammatory bowel disease (IBD) has been revolutionized for the last 10 years by the increasing use of immunomodulators and biologics. With immunosuppression of this kind, opportunistic infection is an important safety concern for patients with IBD. In particular, viral hepatitis is determined by the interaction between the virus and the host’s immunity, and the risk of reactivation increases if immunity is compromised by immunosuppression therapy. Parts of Asia, including Korea, still show intermediate endemicity for the hepatitis A virus and hepatitis B virus compared with the United States and Western Europe. Thus, members of IBD research group of the Korean Association for the Study of Intestinal Diseases have produced a guideline on the prevention and management of viral hepatitis in IBD.

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Iranian Consensus Guideline for Pharmacotherapy with Biologics and Small Molecules Drugs in Adults with Inflammatory Bowel Diseases
Niloofar Khoshnam-Rad, Homayoon Vahedi, Anahita Sadeghi, Mansoor Rastegarpanah, Soha Namazi, Amir Anushiravani, Ali Reza Sima, Shabnam Shahrokh, Sudabeh Alatab, Reza Malekzadeh
Middle East Journal of Digestive Diseases.2023; 15(2): 83. CrossRef
Protective role of flavonoids quercetin and silymarin in the viral-associated inflammatory bowel disease: an updated review
Elham Zarenezhad, Hussein T. Abdulabbas, Ahmed Shayaa Kareem, Seyed Amin Kouhpayeh, Silvia Barbaresi, Sohrab Najafipour, Abdulbaset Mazarzaei, Mitra Sotoudeh, Abdolmajid Ghasemian
Archives of Microbiology.2023;[Epub] CrossRef
The impact of medication belief on adherence to infliximab in patients with Crohn’s disease
Shuyan Li, Yan Ma, Hongling Sun, Zijun Ni, Shurong Hu, Yan Chen, Meijuan Lan
Frontiers in Pharmacology.2023;[Epub] CrossRef
SARS-CoV-2 vaccination for adult patients with inflammatory bowel disease: expert consensus statement by KASID
Yoo Jin Lee, Seong-Eun Kim, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Jae Gon Lee, Hee Chan Yang, Miyoung Choi, Seung-Jae Myung
Intestinal Research.2022; 20(2): 171. CrossRef
Clinical Course of Hepatitis B Viral Infection in Patients Undergoing Anti-Tumor Necrosis Factor α Therapy for Inflammatory Bowel Disease
Ji Min Lee, Shu-Chen Wei, Kang-Moon Lee, Byong Duk Ye, Ren Mao, Hyun-Soo Kim, Soo Jung Park, Sang Hyoung Park, Eun Hye Oh, Jong Pil Im, Byung Ik Jang, Dae Bum Kim, Ken Takeuchi
Gut and Liver.2022; 16(3): 396. CrossRef
Antiviral Prophylaxis Against Hepatitis B Virus in Patients Treated with Anti-Tumor Necrosis Factor α Agents for Inflammatory Bowel Disease
Eun Ae Kang, Jae Hee Cheon
Gut and Liver.2022; 16(4): 501. CrossRef
Risk of Hepatitis B Virus (HBV) Reactivation in Patients with Immune-Mediated Inflammatory Diseases Receiving Biologics: Focus on the Timing of Biologics after Anti-HBV Treatment
Soo Min Ahn, Jonggi Choi, Byong Duk Ye, Suk-Kyun Yang, Ji Seon Oh, Yong‑Gil Kim, Chang-Keun Lee, Bin Yoo, Sang Hyoung Park, Seokchan Hong
Gut and Liver.2022; 16(4): 567. CrossRef
Inflammatory bowel disease in Korea: epidemiology and pathophysiology
Jung Won Lee, Chang Soo Eun
The Korean Journal of Internal Medicine.2022; 37(5): 885. CrossRef
Viral Hepatitis in Patients with Inflammatory Bowel Disease
Seung Hwan Shin, Sang Hyoung Park
The Korean Journal of Gastroenterology.2022; 80(2): 51. CrossRef
Vaccination strategies for Korean patients with inflammatory bowel disease
Yoo Jin Lee, Eun Soo Kim
The Korean Journal of Internal Medicine.2022; 37(5): 920. CrossRef
Current Status of Opportunistic Infection in Inflammatory Bowel Disease Patients in Asia: A Questionnaire-Based Multicenter Study
Hong Yang, Zhihua Ran, Meng Jin, Jia-Ming Qian
Gut and Liver.2022; 16(5): 726. CrossRef
Do We Have an Opportunity to Avoid Opportunistic Infections in Asian Patients with Inflammatory Bowel Disease?
Suhyun Park, Sang Hyoung Park
Gut and Liver.2022; 16(5): 663. CrossRef
Natural history of inflammatory bowel disease: a comparison between the East and the West
Eun Mi Song, Suk-Kyun Yang
Intestinal Research.2022; 20(4): 418. CrossRef
Hepatobiliary Impairments in Patients with Inflammatory Bowel Diseases: The Current Approach
Vlad Alexandru Ionescu, Gina Gheorghe, Valentin Nicolae Varlas, Ana Maria Alexandra Stanescu, Camelia Cristina Diaconu
Gastroenterology Insights.2022; 14(1): 13. CrossRef
Viral infections in inflammatory bowel disease: Tips and tricks for correct management
Vincenzo Craviotto, Federica Furfaro, Laura Loy, Alessandra Zilli, Laurent Peyrin-Biroulet, Gionata Fiorino, Silvio Danese, Mariangela Allocca
World Journal of Gastroenterology.2021; 27(27): 4276. CrossRef
SARS-CoV-2 Vaccination for Adult Patients with Inflammatory Bowel Disease: Expert Consensus Statements by KASID
Yoo Jin Lee, Seong-Eun Kim, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Jae Gon Lee, Hee Chan Yang, Miyoung Choi, Seung-Jae Myung
The Korean Journal of Gastroenterology.2021; 78(2): 117. CrossRef
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Suk-Kyun Yang
Journal of the Korean Medical Association.2021; 64(9): 572. CrossRef
A clinical case of ulcerative colitis in a patient with viral hepatitis
E. D. Kosmachova, M. S. Iakovenko, K. A. Yumukian
South Russian Journal of Therapeutic Practice.2020; 1(3): 95. CrossRef

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18 Crossref

Inflammatory bowel diseases

Pediatric to adult inflammatory bowel disease transition: the Asian experience: Bernice Tan, David Ong; Intest Res 2020;18(1):11-17. Published online January 30, 2020; DOI: https://doi.org/10.5217/ir.2019.09144

Abstract PDF PubReader ePub

Many tertiary inflammatory bowel disease (IBD) centers recognize that a structured transition program is fundamental for an IBD unit. However, the path to ensuring a seamless transition for all stakeholders is often fraught with challenges. In this review, we go through current evidence, identify the requirementsof a successful transition program, and the barriers to seamless transfer. We also aim to shed light on differences in needs between the Western and Asian adolescent IBD populations. Majority of healthcare providers viewed having a structured transition program to be very important. The lack of a standard protocol led us to come up with a list of requirements ofa successful program. These include: multidisciplinary team meetings, alternating visits between the adultand pediatric clinics, proper documentation of records, and determining the ideal timing for transfer. The difficulties forthe Asian adolescent IBD population may be attributed to the reliance on parental support to make decisions regarding medicaltreatment. Lastly, there are various physician, patient and disease factors which are barriers to seamless transition. These includethe lack of proper documentation, and lack of patient self-efficacy. We also propose a standardized template for documentation of medical records for IBD patients.

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Systematic Review: Practices and Programs in Inflammatory Bowel Disease Transition Care
Patrick Chan, Jack McNamara, Angharad Vernon-Roberts, Edward M Giles, Rachael Havrlant, Britt Christensen, Amanda Thomas, Astrid-Jane Williams
Inflammatory Bowel Diseases.2024;[Epub] CrossRef
Current perspectives on pediatric inflammatory bowel disease focusing on transitional care management. What should we consider?
Constanza Bay M, Paulina Núñez F, Rodrigo Quera, Andrés J. Yarur
Gastroenterología y Hepatología.2023; 46(2): 139. CrossRef
Current perspectives on pediatric inflammatory bowel disease focusing on transitional care management. What should we consider?
Constanza Bay M, Paulina Núñez F, Rodrigo Quera, Andrés J. Yarur
Gastroenterología y Hepatología (English Edition).2023; 46(2): 139. CrossRef
Characteristics and Treatment Outcomes of Transition among Patients with Inflammatory Bowel Disease
Eun Jin Yoo, Sang-Hoon Cho, Soo Jung Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Yonsei Medical Journal.2023; 64(9): 541. CrossRef
Clinical Features and Long-Term Outcomes of Paediatric-Onset Inflammatory Bowel Disease in a Population-Based Cohort in the Songpa-Kangdong District of Seoul, Korea
Sang Hyoung Park, Jong Pil Im, Hyunju Park, Seung Kyu Jeong, Ji Hyun Lee, Kyoung Hoon Rhee, Young-Ho Kim, Sung Noh Hong, Kyung Ho Kim, Seung In Seo, Jae Myung Cha, Sun Yong Park, Joo Sung Kim, Hyuk Yoon, Sung Hoon Kim, Jisun Jang, Jeong Hwan Kim, Seong O
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A consensus statement on health‐care transition for childhood‐onset inflammatory bowel disease patients
Hideki Kumagai, Toshiaki Shimizu, Itaru Iwama, Shin‐Ichiro Hagiwara, Takahiro Kudo, Michiko Takahashi, Takeshi Saito, Reiko Kunisaki, Motoi Uchino, Sakiko Hiraoka, Makoto Naganuma, Ken Sugimoto, Jun Miyoshi, Tomoyoshi Shibuya, Tadakazu Hisamatsu
Pediatrics International.2022;[Epub] CrossRef
Vaccination strategies for Korean patients with inflammatory bowel disease
Yoo Jin Lee, Eun Soo Kim
The Korean Journal of Internal Medicine.2022; 37(5): 920. CrossRef
Transition of adult patients with pediatric orthostatic intolerance from child-centered care to adult-centered care
Yoshitoki Yanagimoto
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Transitional care for inflammatory bowel disease: A survey of Japanese pediatric gastroenterologists
Hideki Kumagai, Takahiro Kudo, Keiichi Uchida, Reiko Kunisaki, Akira Sugita, Yoshikazu Ohtsuka, Katsuhiro Arai, Mitsuru Kubota, Hitoshi Tajiri, Yasuo Suzuki, Toshiaki Shimizu
Pediatrics International.2021; 63(1): 65. CrossRef
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Kai Liang Teh, Sook Fun Hoh, Thaschawee Arkachaisri
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How Can We Do Transition Successfully from Pediatric to Adult Clinics in Inflammatory Bowel Disease?
Mi Jin Kim, Sung Noh Hong, Young-Ho Kim, Yon Ho Choe
The Korean Journal of Gastroenterology.2021; 77(5): 227. CrossRef
Transition Services for Pediatric Inflammatory Bowel Disease: Ready for Asian Patients Yet?
Suk-Kyun Yang, Sang Hyoung Park, Byong Duk Ye
Journal of Pediatric Gastroenterology & Nutrition.2021; 73(4): e107. CrossRef
Transitional Care for Patients with Inflammatory Bowel Disease: Japanese Experience
Hideki Kumagai, Yasuo Suzuki, Toshiaki Shimizu
Digestion.2021; 102(1): 18. CrossRef

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145 Download
13 Web of Science
13 Crossref

Inflammatory bowel diseases

Update of endoscopic management of Crohn’s disease strictures: Akshay Pokala, Bo Shen; Intest Res 2020;18(1):1-10. Published online January 30, 2020; DOI: https://doi.org/10.5217/ir.2019.09158

Abstract PDF PubReader ePub

One of the most common complications of Crohn’s disease (CD) is the formation of strictures. Endoscopy plays a vital role not only in the diagnosis, differential diagnosis, and disease monitoring of CD, but also the delivery of effective treatment. The purpose of this review is to update the endoscopic management of strictures in CD. Endoscopic therapy has provided minimally invasive treatment for CD. Commonly used endoscopic treatment modalities include balloon dilation, endoscopic stricturotomy, endoscopic strictureplasty, and endoscopic stenting. The pros and cons of these endoscopic treatment modalities are discussed.

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Increasing Rates of Bowel Resection Surgery for Stricturing Crohn’s Disease in the Biologic Era
Kush Fansiwala, Ellen J Spartz, Andrew R Roney, Mary R Kwaan, Jenny S Sauk, Po-Hung Chen, Berkeley N Limketkai
Inflammatory Bowel Diseases.2024;[Epub] CrossRef
Clinical outcomes of serial endoscopic balloon dilation for duodenal Crohn’s disease-associated strictures
Juanjuan Zhang, Xiaoli Qian, Lin Zhu, Binlin Da, Xiaofan Zhao, Qin He, Lixin Wang, Yi Li, Zhiming Wang
Surgical Endoscopy.2024; 38(8): 4512. CrossRef
Endoscopic Management of Strictures in Crohn’s Disease: An Unsolved Case
Gaetano Coppola, Chiara Principessa, Federica Di Vincenzo, Pierluigi Puca, Angelo Del Gaudio, Ivan Capobianco, Bianca Bartocci, Alfredo Papa, Giovanni Cammarota, Loris Riccardo Lopetuso, Franco Scaldaferri
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The Promise of Single-Cell RNA Sequencing to Redefine the Understanding of Crohn’s Disease Fibrosis Mechanisms
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How to Prevent and Treat the Most Frequent Adverse Events Related to Luminal Dilation and Stenting in Benign Disease
Eduardo Rodrigues-Pinto, Joel Ferreira-Silva, Peter D. Siersema
American Journal of Gastroenterology.2023; 118(9): 1521. CrossRef
Crohn's disease: an update
Ella Cockburn, Shahed Kamal, Andrea Chan, Vikram Rao, Tianwei Liu, Joanna Y Huang, Jonathan P Segal
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Carme Loras, Miriam Mañosa, Xavier Andújar, Vicente Sánchiz, Marc Martí-Gallostra, Yamile Zabana, Ana Gutiérrez, Manuel Barreiro-de Acosta
Gastroenterología y Hepatología.2022; 45(4): 315. CrossRef
Endoscopic Balloon Dilation Is Cost-Effective for Crohn’s Disease Strictures
Kate E. Lee, Francesca Lim, Adam S. Faye, Bo Shen, Chin Hur
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Position Statement. Recommendations of the Spanish Group on Crohn’s Disease and Ulcerative Colitis (GETECCU) on the treatment of strictures in Crohn’s disease
Carme Loras, Miriam Mañosa, Xavier Andújar, Vicente Sánchiz, Marc Martí-Gallostra, Yamile Zabana, Ana Gutiérrez, Manuel Barreiro-de Acosta
Gastroenterología y Hepatología (English Edition).2022; 45(4): 315. CrossRef
Endoscopic activity in inflammatory bowel disease: clinical significance and application in practice
Kyeong Ok Kim
Clinical Endoscopy.2022; 55(4): 480. CrossRef
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Amr M. Arar, Kelli DeLay, David A. Leiman, Paul Menard-Katcher
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Active Assessment of Inflammatory Bowel Disease
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Long-Term Outcome of Endoscopic Balloon Dilation for Duodenal Crohn’s Disease-Associated Strictures
Juanjuan Zhang, Yi Li, Yanqing Diao, Binlin Da, Zhiming Wang
Digestive Diseases and Sciences.2021; 66(10): 3570. CrossRef
Story of strictures, stents, and many more
Saiprasad Girish Lad, Kailash M. Kolhe, Shamshersingh G. Chauhan, Meghraj A. Ingle, Mayur Gattani, Harshad Khairnar
Gastrointestinal Endoscopy.2021; 93(2): 535. CrossRef
Enteroscopy in Crohn’s Disease: Are There Any Changes in Role or Outcomes Over Time? A KASID Multicenter Study
Seong Ran Jeon, Jin-Oh Kim, Jeong-Sik Byeon, Dong-Hoon Yang, Bong Min Ko, Hyeon Jeong Goong, Hyun Joo Jang, Soo Jung Park, Eun Ran Kim, Sung Noh Hong, Jong Pil Im, Seong-Eun Kim, Ja Seol Koo, Chang Soo Eun, Dong Kyung Chang
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Managing Stricturing Crohn's Disease: Resect? Strictureplasty? Dilate?
Lea Lowenfeld, Fabrizio Michelassi
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Crohn’s disease at radiological imaging: focus on techniques and intestinal tract
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273 Download
14 Web of Science
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Colorectal neoplasia

Prevalence and risk factors of colorectal cancer in Asia: Martin CS Wong, Hanyue Ding, Jingxuan Wang, Paul SF Chan, Junjie Huang; Intest Res 2019;17(3):317-329. Published online May 20, 2019; DOI: https://doi.org/10.5217/ir.2019.00021

Abstract PDF PubReader ePub

Globally, colorectal cancer (CRC) is a substantial public health burden, and it is increasingly affecting populations in Asian countries. The overall prevalence of CRC is reported to be low in Asia when compared with that in Western nations, yet it had the highest number of prevalent cases. This review described the prevalence of CRC in Asia according to the International Agency for Research on Cancer from World Health Organization (WHO) database and summarized its major risk factors. Non-modifiable factors include genetic factors, ethnicity, age, gender, family history and body height; smoking, alcohol drinking, weight, Westernized diet, physical inactivity, chronic diseases and microbiota were involved in environmental factors. These risk factors were separately discussed in this review according to published literature from Asian countries. CRC screening has been playing an important role in reducing its disease burden. Some recommendations on its screening practices have been formulated in guidelines for Asia Pacific countries.

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Akiko Hanyuda, Atsushi Goto, Ryoko Katagiri, Yuriko N. Koyanagi, Masahiro Nakatochi, Yoichi Sutoh, Shiori Nakano, Isao Oze, Hidemi Ito, Taiki Yamaji, Norie Sawada, Masao Iwagami, Aya Kadota, Teruhide Koyama, Sakurako Katsuura-Kamano, Hiroaki Ikezaki, Keit
Scientific Reports.2023;[Epub] CrossRef
Recent Progress and Perspective of an Evolving Carbon Family From 0D to 3D: Synthesis, Biomedical Applications, and Potential Challenges
Wenhui Yi, Asif Khalid, Naila Arshad, M. Sohail Asghar, Muhammad Sultan Irshad, Xianbao Wang, Yueyang Yi, Jinhai Si, Xun Hou, Hong Rong Li
ACS Applied Bio Materials.2023; 6(6): 2043. CrossRef
Changing Colorectal Cancer Trends in Asians: Epidemiology and Risk Factors
Carissa Ikka Pardamean, Digdo Sudigyo, Arif Budiarto, Bharuno Mahesworo, Alam Ahmad Hidayat, James W. Baurley, Bens Pardamean
Oncology Reviews.2023;[Epub] CrossRef
Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with metastatic colorectal cancer
T. Yoshino, A. Cervantes, H. Bando, E. Martinelli, E. Oki, R.-H. Xu, N.A. Mulansari, K. Govind Babu, M.A. Lee, C.K. Tan, G. Cornelio, D.Q. Chong, L.-T. Chen, S. Tanasanvimon, N. Prasongsook, K.-H. Yeh, C. Chua, M.D. Sacdalan, W.J. Sow (Jenson), S.T. Kim,
ESMO Open.2023; 8(3): 101558. CrossRef
Gut Microbiota and Colorectal Cancer Risk Factors
Hadi Feizi, Mohammad Ahangarzadeh Rezaee, Reza Ghotaslou, Mohammad Sadrkabir, Farhad Jadidi-Niaragh, Pourya Gholizadeh, Sepehr Taghizadeh, Khudaverdi Ghanbarov, Mehdi Yousefi, Hossein Samadi Kafil
Current Pharmaceutical Biotechnology.2023; 24(8): 1018. CrossRef
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Fatemeh Ghasemi-Kebria, Nastaran Jafari-Delouie, Shahryar Semnani, Abdolreza Fazel, Arash Etemadi, Alireza Norouzi, Reza Khandoozi, Sima Besharat, Nesa Shokouhifar, Honyehsadat Mirkarimi, SeyyedMehdi Sedaghat, Mohsen Mansoury, Mahshid Mehrjerdian, Elisabe
Cancer Epidemiology.2023; 86: 102415. CrossRef
Smoking and risk of colorectal cancer according to KRAS and BRAF mutation status in a Japanese prospective Study
Shiori Nakano, Taiki Yamaji, Kouya Shiraishi, Akihisa Hidaka, Taichi Shimazu, Aya Kuchiba, Masahiro Saito, Fumihito Kunishima, Ryouji Nakaza, Takashi Kohno, Norie Sawada, Manami Inoue, Shoichiro Tsugane, Motoki Iwasaki
Carcinogenesis.2023; 44(6): 476. CrossRef
Effects of ranitidine and nizatidine on the risk of gastrointestinal cancer
Hyejung Kang, Chung Mo Nam, Dong-Woo Choi, Sohee Park
Frontiers in Oncology.2023;[Epub] CrossRef
Prevalence, Microbiological Profile, and Risk Factors of Surgical Site Infections in Saudi Patients with Colorectal Cancer
Marwh Gassim Aldriwesh, Abrar Alnodley, Norah Almutairi, Mohammed Algarni, Ayyob Alqarni, Bayan Albdah, Mutaib Mashraqi
Saudi Journal of Medicine & Medical Sciences.2023; 11(3): 208. CrossRef
Schistosoma japonicum Associated Colorectal Cancer and Its Management
Sidhant Jain, Meenakshi Rana, Pooja Choubey, Sahil Kumar
Acta Parasitologica.2023; 68(4): 723. CrossRef
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Alexandru Isaic, Alexandru Cătălin Motofelea, Dan Costachescu, Gheorghe Nicusor Pop, Bogdan Totolici, Dorel Popovici, Razvan Gheorghe Diaconescu
Healthcare.2023; 11(16): 2347. CrossRef
Ras-Related Protein Rap1A Accelerates the Malignant Process of Colorectal Carcinoma via Activating Fibroblast Growth Factor-2
Xuezhong Liu, Qiuyuan Wang
Journal of Biomedical Nanotechnology.2023; 19(7): 1301. CrossRef
Relationship between metalloproteinase-9 (MMP-9) expression and clinicopathology in colorectal cancer: a cross-sectional study
Mudatsir, Ibrahim Labeda, Julianus Aboyaman Uwuratuw, Joko Hendarto, Warsinggih, Ronald Erasio Lusikooy, Mappincara, Samuel Sampetoding, Muhammad Ihwan Kusuma, Erwin Syarifuddin, Arham Arsyad, Muhammad Faruk
Annals of Medicine & Surgery.2023; 85(9): 4277. CrossRef
Probiotics as a Therapeutic Approach in Colorectal Cancer
Nafiseh Rahmani, Ghazaleh Pourali, Nayyerehalsadat Hosseini, Hamid Fiuji, Mina Maftooh, Seyed Mahdi Hassanian, Gordon A Ferns, Majid Khazaei, Amir Avan
Current Cancer Drug Targets.2023; 23(10): 764. CrossRef
Zinc intake, SLC30A8 rs3802177 polymorphism, and colorectal cancer risk in a Korean population: a case–control study
Linh Thi Dieu Nguyen, Madhawa Gunathilake, Jeonghee Lee, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin, Jeongseon Kim
Journal of Cancer Research and Clinical Oncology.2023; 149(18): 16429. CrossRef
Role of Lactobacillus and calcium in colorectal cancer
Hemant Devidas Une, Mrudula Yogesh Kumavat, Amar Bhagwan Shirsat
Indian Journal of Pathology and Oncology.2023; 10(3): 224. CrossRef
You are not lab rats at teaching hospitals: A systematic review of resident and fellow participation leads to improved colonoscopy
Chenyu Sun, Yue Chen, Shaodi Ma, Mengqing Liu, Vicky Yau, Na Hyun Kim, Sujatha Kailas, Scott Lowe, Rachel Bentley, Shuya Chen, Jie Liu, Muzi Meng, Yuting Huang, Qin Zhou, Yuyan Wu
Journal of Evidence-Based Medicine.2023; 16(3): 332. CrossRef
A novel proteomic-based model for predicting colorectal cancer with Schistosoma japonicum co‐infection by integrated bioinformatics analysis and machine learning
Shan Li, Xuguang Sun, Ting Li, Yanqing Shi, Binjie Xu, Yuyong Deng, Sifan Wang
BMC Medical Genomics.2023;[Epub] CrossRef
Implications of single-cell immune landscape of tumor microenvironment for the colorectal cancer diagnostics and therapy
Ahmad Alzamami
Medical Oncology.2023;[Epub] CrossRef
The association between empirical dietary inflammatory pattern and colorectal cancer risk: a case-control study
Zainab Shateri, Maede Makhtoomi, Fatemeh Mansouri, Milad Rajabzadeh-dehkordi, Mehran Nouri, Bahram Rashidkhani
BMC Nutrition.2023;[Epub] CrossRef
ABO and Rhesus blood group markers as predictors in colorectal cancer: A prospective observational study
Gowhar Rashid, Gulzar A. Bhat, Tahseen Bilal Rather, Kulsum Akhtar, Ishrat Parveiz, Syed Nisar Ahmad, Malik Tariq Rasool, Farooq Ahmad Jan, Mohanad Diab, Wael Hafez, Syed Mudassar
Medicine.2023; 102(47): e36256. CrossRef
Impact of alcohol consumption on risk of colorectal cancer in Eastern Mediterranean Regional Office (EMRO) countries: a systematic review and meta-analysis
Mohammad-Hossein Keivanlou, Ehsan Amini-Salehi, Farahnaz Joukar, Naeim Norouzi, Negin Letafatkar, Arman Habibi, Fariborz Mansour-Ghanaei, Maryam Sadat Aleali, Mohammad Taghi Ashoobi, Soheil Hassanipour
Journal of Public Health.2023;[Epub] CrossRef
Rosemary as a Potential Source of Natural Antioxidants and Anticancer Agents: A Molecular Docking Study
Haytham Bouammali, Linda Zraibi, Imane Ziani, Mohammed Merzouki, Lamiae Bourassi, Elmehdi Fraj, Allal Challioui, Khalil Azzaoui, Rachid Sabbahi, Belkheir Hammouti, Shehdeh Jodeh, Maryam Hassiba, Rachid Touzani
Plants.2023; 13(1): 89. CrossRef
EBP50 Depletion and Nuclear β-Catenin Accumulation Engender Aggressive Behavior of Colorectal Carcinoma through Induction of Tumor Budding
Takashi Itou, Yu Ishibashi, Yasuko Oguri, Miki Hashimura, Ako Yokoi, Yohei Harada, Naomi Fukagawa, Misato Hayashi, Mototsugu Ono, Chika Kusano, Makoto Saegusa
Cancers.2023; 16(1): 183. CrossRef
Raptinal ameliorates 1,2-dimethylhydrazine-induced colon cancer through p53/Bcl2/Bax/caspase-3-mediated apoptotic events in vitro and in vivo
Yongting Lan, Yang Yang, Abhijit Das, Barshana Bhattacharya, Souvik Roy
Indian Journal of Pharmacology.2023; 55(2): 97. CrossRef
Chemopreventive effects of anthocyanins on colorectal and breast cancer: A review
David Bars-Cortina, Ali Sakhawat, Carme Piñol-Felis, María-Jose Motilva
Seminars in Cancer Biology.2022; 81: 241. CrossRef
A 10-year registry-based incidence, mortality, and survival analysis of colorectal cancer in Northern Malaysia
Ibtisam Ismail, HuanKeat Chan, SoelarShahrul Aiman, AbuHassan Muhammad Radzi
Journal of Cancer Research and Therapeutics.2022; 18(4): 931. CrossRef
Risk of developing metachronous colorectal neoplasia after the resection of proximal versus distal adenomas
Yoon Suk Jung, Nam Hee Kim, Youngwoo Kim, Dong Il Park
Digestive and Liver Disease.2022; 54(4): 537. CrossRef
Positive fecal immunochemical test results are associated with non-colorectal cancer mortality
Yoon Suk Jung, Jinhee Lee, Chang Mo Moon
The Korean Journal of Internal Medicine.2022; 37(2): 313. CrossRef
Sessile serrated lesions in patients with adenoma on index colonoscopy do not increase metachronous advanced adenoma risk
Seung Wook Hong, Jeongseok Kim, Ji Young Lee, Jong‐Soo Lee, Hye‐Sook Chang, Hye Won Park, Gwang‐Un Kim, Jiyoung Yoon, Byong Duk Ye, Jeong‐Sik Byeon, Seung‐Jae Myung, Suk‐Kyun Yang, Jaewon Choe, Dong‐Hoon Yang
Digestive Endoscopy.2022; 34(4): 850. CrossRef
Impact of antiplatelet agents and anticoagulants on the performance of fecal immunochemical tests: a systematic review and meta-analysis
Yoon Suk Jung, Eui Im, Chan Hyuk Park
Surgical Endoscopy.2022; 36(6): 4299. CrossRef
Efficacy and safety of split-dose bowel preparation with 1 L polyethylene glycol and ascorbate compared with 2 L polyethylene glycol and ascorbate in a Korean population: a phase IV, multicenter, randomized, endoscopist-blinded study
Sung Noh Hong, Chang Kyun Lee, Jong Pil Im, Chang Hwan Choi, Jeong-Sik Byeon, Young-Seok Cho, Sung-Ae Jung, Tae Il Kim, Yoon Tae Jeen
Gastrointestinal Endoscopy.2022; 95(3): 500. CrossRef
The role of anaerobic bacteria in the development and prevention of colorectal cancer: A review study
Mehrdad Mohammadi, Hamed Mirzaei, Mitra Motallebi
Anaerobe.2022; 73: 102501. CrossRef
Prevalence and associated risk of advanced colorectal neoplasia in adults with sarcopenia
Min Cheol Kim, Kyeong Ok Kim, Min Kyu Kang
The Korean Journal of Internal Medicine.2022; 37(2): 294. CrossRef
Factors associated with positive predictive value of preliminary screening in a two-step screening strategy for colorectal neoplasms in China
Ji-Bin Li, Zhi-Yu Qiu, Yu-Xiang Deng, Yin Li, Zhuo-Chen Lin, Yan-Ping Wu, Fan Weng, Huan Tian, Qing-Jian Ou, Cheng-Hua Gong, Zhi-Zhong Pan, De-Sen Wan, Jian-Hong Peng, Yu-Jing Fang
Discover Oncology.2022;[Epub] CrossRef
Amelioration of DMH-induced colon cancer by eupafolin through the reprogramming of apoptosis-associated p53/Bcl2/Bax signaling in rats
Congcong Wang, Xiao Qiao, Jingwen Wang, Jia Yang, Chen Yang, Yi Qiao, Yue Guan, Aidong Wen, Liuqin Jiang
European Journal of Inflammation.2022; 20: 205873922110697. CrossRef
Colorectal cancer patients advocating screening to their siblings: a randomized behavioral intervention
Lina Choe, Jerrald Lau, Si-Ying Fong, Emily Chew, Wen-Min Chow, Yan Pang, Tian-Zhi Lim, Choon-Seng Chong, Min-Hoe Chew, Fung-Joon Foo, Frederick Hong-Xiang Koh, Mee-Lian Wong, Gerald Choon-Huat Koh, Ker-Kan Tan
Gastrointestinal Endoscopy.2022; 95(3): 519. CrossRef
Immune profile by multiplexed immunohistochemistry associated with recurrence after chemoradiation in rectal cancer
Seung Wook Hong, Seohyun Lee, Yun Jae Kim, Soyeon Ahn, In Ja Park, Seung‐Mo Hong, Sung Wook Hwang, Sang Hyoung Park, Dong‐Hoon Yang, Byong Duk Ye, Jeong‐Sik Byeon, Suk‐Kyun Yang, Jaeil Kim, Sang‐Yeob Kim, Seung‐Jae Myung
Journal of Gastroenterology and Hepatology.2022; 37(3): 542. CrossRef
Screening and Evaluation of Probiotics for Reducing Intestinal Inflammation
雅君陈
Hans Journal of Food and Nutrition Science.2022; 11(01): 44. CrossRef
Factors Associated With Colorectal Cancer Screening Among First-Degree Relatives of Patients With Colorectal Cancer in China
Qianqian Du, Jingyu Chen, Ya Meng, Ni Gong, Xiaodan Wu, Qiyuan Lyu, Yiheng Zhang, Xiaoyu Wu, Meifen Zhang
Cancer Nursing.2022; 45(2): E447. CrossRef
Detection and isolation of typical gut indigenous bacteria in mice fed corn starch, bread flour or whole wheat flour
Natsumi Takei, Takashi Kuda, Natsumi Handa, Hajime Takahashi, Bon Kimura
Food Bioengineering.2022; 1(1): 91. CrossRef
Locations and histopathology of colorectal polyps in Turkey: experiences of two centers
Zeynep S. BAHCE, Serdar GUMUS, Ebral YIGIT
Chirurgia.2022;[Epub] CrossRef
Risk of Metachronous Colorectal Advanced Neoplasia and Cancer in Patients With 3–4 Nonadvanced Adenomas at Index Colonoscopy: A Systematic Review and Meta-Analysis
Suyeon Park, Seong Ran Jeon, Hyun Gun Kim, Yunho Jung, Min-Seob Kwak, Su Young Kim, Jong Wook Kim, Seung-Joo Nam, Eun Hye Oh, Seon-Young Park, Soo-Kyung Park, Jeong-Sik Byeon, Sun-Jin Boo, Dong Hoon Baek, Soon Man Yoon, Jaeyoung Chun, Jooyoung Lee, Miyoun
American Journal of Gastroenterology.2022; 117(4): 588. CrossRef
Can Computed Tomography Colonography Replace Optical Colonoscopy in Detecting Colorectal Lesions?: State of the Art
Alessia Chini, Michele Manigrasso, Grazia Cantore, Rosa Maione, Marco Milone, Francesco Maione, Giovanni Domenico De Palma
Clinical Endoscopy.2022; 55(2): 183. CrossRef
Meta-Analysis of the Association between Dietary Inflammatory Index (DII) and Colorectal Cancer
Sharifah Saffinas Syed Soffian, Azmawati Mohammed Nawi, Rozita Hod, Mohd Hasni Ja’afar, Zaleha Md Isa, Huan-Keat Chan, Muhammad Radzi Abu Hassan
Nutrients.2022; 14(8): 1555. CrossRef
Report of 13-year survival of patients with colon and rectal cancers; lessons from Shiraz colorectal cancer surgery registry system of a level three medical center
Ali Reza Safarpour, Alimohammad Bananzadeh, Ahmad Izadpanah, Leila Ghahramani, Seyed Mohammad Kazem Tadayon, Faranak Bahrami, Seyed Vahid Hosseini
BMC Surgery.2022;[Epub] CrossRef
Effects of Jianpi Lishi Jiedu granules on colorectal adenoma patients after endoscopic treatment: study protocol for a randomized, double-blinded, placebo-controlled clinical trial
Hao Wu, Yuzhen Huang, Lu Yang, Kunhan Su, Shuo Tian, Xin Chen, Siyu Li, Wanli Liu
Trials.2022;[Epub] CrossRef
Anticancer Properties of Curcumin Against Colorectal Cancer: A Review
Oluwafemi Adeleke Ojo, Temiloluwa Rhoda Adeyemo, Damilare Rotimi, Gaber El-Saber Batiha, Gomaa Mostafa-Hedeab, Matthew Eboseremen Iyobhebhe, Tobiloba Christiana Elebiyo, Bukola Atunwa, Adebola Busola Ojo, Clara Mariana Goncalves Lima, Carlos Adam Conte-Ju
Frontiers in Oncology.2022;[Epub] CrossRef
Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin
Ruting Zhong, Mohamed A. Farag, Meiwan Chen, Chengwei He, Jianbo Xiao
eFood.2022;[Epub] CrossRef
The Influence of Face Shields on the Quality of Colonoscopy in the Era of the COVID-19 Pandemic
Jin Wook Lee, Hyo Jeong Lee, Dae Sung Kim, Jiyoung Yoon, Seung Wook Hong, Ha Won Hwang, Jong-Soo Lee, Gwang-Un Kim, Sinwon Lee, Jaewon Choe, Jin Hwa Park, Dong-Hoon Yang, Jeong-Sik Byeon
Gut and Liver.2022; 16(3): 404. CrossRef
rs401502 and rs11575934 Polymorphisms of the IL-12 Receptor Beta 1 Gene are Protective Against Colorectal Carcinogenesis
Refka Jelassi, Sabrine Dhouioui, Hamza Ben Salah, Nasreddine Saidi, Nabiha Mzoughi, Radhia Ammi, Aida Bouratbine, Karim Aoun, Ines Zidi, Hanen Chelbi
Frontiers in Genetics.2022;[Epub] CrossRef
Quality indicators in colonoscopy: the chasm between ideal and reality
Su Bee Park, Jae Myung Cha
Clinical Endoscopy.2022; 55(3): 332. CrossRef
Tumor Detection on Microarray Data Using Grey Wolf Optimization with Gain Information
K. Dhana Sree Devi, P. Karthikeyan, Usha Moorthy, K. Deeba, V. Maheshwari, Shaikh Muhammad Allayear, Shimin Wang
Mathematical Problems in Engineering.2022; 2022: 1. CrossRef
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Hafeez Afolabi, Salzihan Md Salleh, Zaidi Zakaria, Ch’ng Ewe Seng, Siti Norasikin Binti Mohd Nafil, Ahmad Aizat Bin Abdul Aziz, Yusuf Wada, Ahmad Irekeola, Syed Sameer Aga
BioMed Research International.2022; 2022: 1. CrossRef
Title: Involvement of unsaturated fatty acid biosynthesis in CRC progression based on in vitro and in silico studies
Khatere Mokhtari, Mohammad Mahdevar, Maral Hajipour, Maryam Esmaeili, Maryam Peymani, Sepideh Mirzaei, Mohammad Hossein Nasr-Esfahani, Mehrdad Hashemi, Kiavash Hushmandi, Kamran Ghaedi
Biomedicine & Pharmacotherapy.2022; 153: 113338. CrossRef
Anti-inflammatory and Antioxidant Effect of Lycoperoside H against the 1,2-Dimethyl Hydrazine (DMH) Induced Colorectal Cancer in Rats
Yongjian Liu, Xin Qi
Journal of Oleo Science.2022; 71(7): 1021. CrossRef
Utility of artificial intelligence with deep learning of hematoxylin and eosin-stained whole slide images to predict lymph node metastasis in T1 colorectal cancer using endoscopically resected specimens; prediction of lymph node metastasis in T1 colorecta
Joo Hye Song, Yiyu Hong, Eun Ran Kim, Seok-Hyung Kim, Insuk Sohn
Journal of Gastroenterology.2022; 57(9): 654. CrossRef
Plant-derived bioactive compounds in colon cancer treatment: An updated review
Akanksha Esmeeta, Subhamay Adhikary, V. Dharshnaa, P. Swarnamughi, Z. Ummul Maqsummiya, Antara Banerjee, Surajit Pathak, Asim K. Duttaroy
Biomedicine & Pharmacotherapy.2022; 153: 113384. CrossRef
Harmol alleviates dimethylhydrazine induced colon cancer by downregulating Bcl2/IL-6/TNF-α expression in association with p53 mediated apoptosis
Ni Guo, Jie Gao
European Journal of Inflammation.2022; 20: 1721727X2211100. CrossRef
Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians
Jie Ping, Yaohua Yang, Wanqing Wen, Sun‐Seog Kweon, Koichi Matsuda, Wei‐Hua Jia, Aesun Shin, Yu‐Tang Gao, Keitaro Matsuo, Jeongseon Kim, Dong‐Hyun Kim, Sun Ha Jee, Qiuyin Cai, Zhishan Chen, Ran Tao, Min‐Ho Shin, Chizu Tanikawa, Zhi‐Zhong Pan, Jae Hwan Oh,
International Journal of Cancer.2022; 151(10): 1726. CrossRef
The emerging era of personalized medicine in advanced colorectal cancer
Claudia W K Wu, Madeleine Reid, Simon Leedham, Rashid N Lui
Journal of Gastroenterology and Hepatology.2022; 37(8): 1411. CrossRef
Crosstalk between mucosal microbiota, host gene expression, and sociomedical factors in the progression of colorectal cancer
Namjoo Kim, Jeong-An Gim, Beom Jae Lee, Byung il Choi, Hee Sook Yoon, Seung Han Kim, Moon Kyung Joo, Jong-Jae Park, Chungyeul Kim
Scientific Reports.2022;[Epub] CrossRef
Long-Time Trend of Colorectal Cancer Mortality Attributable to High Processed Meat Intake in China and a Bayesian Projection from 2020 to 2030: A Model-Based Study
Fangyao Chen, Shiyu Chen, Yaqi Luo, Aima Si, Yuhui Yang, Yemian Li, Weiwei Hu, Yuxiang Zhang
International Journal of Environmental Research and Public Health.2022; 19(17): 10603. CrossRef
Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment
Hazem Choukaife, Salma Seyam, Batoul Alallam, Abd Almonem Doolaanea, Mulham Alfatama
International Journal of Nanomedicine.2022; Volume 17: 3933. CrossRef
Analysing 11 years of incidence trends, clinicopathological characteristics, and forecasts of colorectal cancer in young and old patients: a retrospective cross-sectional study in an Indonesian national referral hospital
Nur Rahadiani, Muhammad Habiburrahman, Murdani Abdullah, Wifanto Saditya Jeo, Marini Stephanie, Diah Rini Handjari, Ening Krisnuhoni
BMJ Open.2022; 12(9): e060839. CrossRef
Colorectal cancer in patients with SARS-CoV-2: a systematic review and meta-analysis
Saad Alhumaid, Abbas Al Mutair, Jawad S. Busubaih, Nourah Al Dossary, Murtadha Alsuliman, Sarah A. Baltyour, Ibrahim Alissa, Hassan I. Al Hassar, Noor A. Al Aithan, Hani A. Albassri, Suliman A. AlOmran, Raed M. ALGhazal, Ahmed Busbaih, Nasser A. Alsalem,
Infectious Agents and Cancer.2022;[Epub] CrossRef
Association between A Family History of Colorectal Cancer and the Risk of Colorectal Cancer: A Nationwide Population-Based Study
Yoon Suk Jung, Huiyeon Song, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
Journal of Personalized Medicine.2022; 12(10): 1566. CrossRef
ERCC1 Overexpression Increases Radioresistance in Colorectal Cancer Cells
Yi-Jung Huang, Ming-Yii Huang, Tian-Lu Cheng, Shih-Hsun Kuo, Chien-Chih Ke, Yi-Ting Chen, Yuan-Chin Hsieh, Jaw-Yuan Wang, Chiu-Min Cheng, Chih-Hung Chuang
Cancers.2022; 14(19): 4798. CrossRef
Dietary Nonstarch Polysaccharide Intake and Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study
Yi-Chuan Yu, Pedram Paragomi, Aizhen Jin, Renwei Wang, Robert E. Schoen, Woon-Puay Koh, Jian-Min Yuan, Hung N. Luu
Cancer Research Communications.2022; 2(10): 1304. CrossRef
Expression of Vascular Endothelial Growth Factor (VEGF) in Colorectal Adenoma and Carcinoma in a Tertiary Care Center
Subalakshmi Balasubramanian, Nagarajan Priyathersini, Thanka Johnson
Cureus.2022;[Epub] CrossRef
Clinicopathological characteristics of high microsatellite instability/mismatch repair-deficient colorectal cancer: A narrative review
Wei-Jian Mei, Mi Mi, Jing Qian, Nan Xiao, Ying Yuan, Pei-Rong Ding
Frontiers in Immunology.2022;[Epub] CrossRef
Diagnosis by Volatile Organic Compounds in Exhaled Breath from Patients with Gastric and Colorectal Cancers
Jinwook Chung, Salima Akter, Sunhee Han, Yoonhwa Shin, Tae Choi, Insug Kang, Sung Kim
International Journal of Molecular Sciences.2022; 24(1): 129. CrossRef
Association between Diet-related Behaviour and Risk of Colorectal Cancer: A Scoping Review
Nur Mahirah Amani Binti Mohammad, Mohd Razif Shahril, Suzana Shahar, Michael Fenech, Razinah Sharif
Journal of Cancer Prevention.2022; 27(4): 208. CrossRef
Inhibition of Cell Proliferation and Induction of Cell Cycle Arrest in Colon Cancer Cells by Lyophilized Mango (Mangifera indicaL.) Pulp Extract
Gustavo Argenor Lozano-Casabianca, Sandra Sulay Arango-Varela, Johanny Aguillón-Osma, María Alejandra Llano-Ramírez, María Elena Maldonado-Celis
Preventive Nutrition and Food Science.2022; 27(4): 436. CrossRef
Hereditary, environmental, and dietary risk factors of colorectal cancer: a case-control study in the Algerian East
Samira Negrichi, Salima Taleb
Environmental Science and Pollution Research.2021; 28(10): 12372. CrossRef
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Je-Ming Hu, Chia-Cheng Lee, Tzu-Chiao Lin, Chi-Hsiang Chung, Chao-Yang Chen, Pi-Kai Chang, Cheng-Wen Hsiao, Chien-An Sun, Nian-Sheng Tzeng, Wu-Chien Chien
Frontiers in Psychiatry.2021;[Epub] CrossRef
Incidence and Risk Factors of Colorectal Cancer in the Iranian Population: a Systematic Review
Hossein Mozafar Saadati, Batool Okhovat, Farzad Khodamoradi
Journal of Gastrointestinal Cancer.2021; 52(2): 414. CrossRef
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Jung Min Moon, Jong Pil Im, Donghee Kim, Yoo Min Han, Hosim Soh, Ji Hyun Song, Sun Young Yang, Young Sun Kim, Jeong Yoon Yim, Seon Hee Lim, Joo Sung Kim
Journal of Gastroenterology and Hepatology.2021; 36(7): 1836. CrossRef
Dietary Intake as Determinant Nongenetic Factors to Colorectal Cancer Incidence and Staging Progression: A Study in South Sulawesi Population, Indonesia
Ika Nurlaila, Alam A. Hidayat, Arif Budiarto, Bharuno Mahesworo, Kartika Purwandari, Bens Pardamean
Nutrition and Cancer.2021; 73(11-12): 2523. CrossRef
Comparison of Risk of Metachronous Advanced Colorectal Neoplasia in Patients with Sporadic Adenomas Aged < 50 Versus ≥ 50 years: A Systematic Review and Meta-Analysis
Yoon Suk Jung, Jung Ho Park, Chan Hyuk Park
Journal of Personalized Medicine.2021; 11(2): 120. CrossRef
Survival of colorectal cancer patients in Brunei Darussalam: comparison between 2002–09 and 2010–17
Shirley H. F. Lee, Hanif Abdul Rahman, Nadiah Abidin, Sok King Ong, Elvynna Leong, Lin Naing
BMC Cancer.2021;[Epub] CrossRef
Schistosoma japonicum Associated With Colorectal Cancer
Anas Almoghrabi, Obaie Mzaik, Bashar Attar
ACG Case Reports Journal.2021; 8(5): e00572. CrossRef
Use of Antiplatelet Agents Decreases the Positive Predictive Value of Fecal Immunochemical Tests for Colorectal Cancer but Does Not Affect Their Sensitivity
Yoonsuk Jung, Eui Im, Jinhee Lee, Hyeah Lee, Changmo Moon
Journal of Personalized Medicine.2021; 11(6): 497. CrossRef
Risk of colorectal cancer in patients with positive results of fecal immunochemical test performed within 5 years since the last colonoscopy
Yoon Suk Jung, Jinhee Lee, Chang Mo Moon
The Korean Journal of Internal Medicine.2021; 36(5): 1083. CrossRef
Strategies for colorectal cancer screening and post-polypectomy surveillance for young adults under age 50
Yoon Suk Jung
Precision and Future Medicine.2021; 5(2): 69. CrossRef
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Chia-Lin Chou, Tzu-Ju Chen, Yu-Feng Tian, Ti-Chun Chan, Cheng-Fa Yeh, Wan-Shan Li, Hsin-Hwa Tsai, Chien-Feng Li, Hong-Yue Lai
Life.2021; 11(7): 646. CrossRef
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Dong-Hoon Yang
The Korean Journal of Internal Medicine.2021; 36(4): 839. CrossRef
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IBD

Stem cell-based therapy for inflammatory bowel disease: Hiromichi Shimizu, Kohei Suzuki, Mamoru Watanabe, Ryuichi Okamoto; Intest Res 2019;17(3):311-316. Published online July 25, 2019; DOI: https://doi.org/10.5217/ir.2019.00043

Abstract PDF PubReader ePub

Inflammatory bowel disease (IBD) is an idiopathic, multi-etiological disease characterized by inflammation and mucosal destruction of the gastrointestinal tract. Despite the remarkable advance in immunomodulating therapies, there still remains a certain population of patients who are refractory to conventional as well as biologic therapies and fail to achieve mucosal healing. To improve the prognosis of those patients, at least 2 types of stem cells have been tested for their potential therapeutic use. Transplantation of hematopoietic stem cells or mesenchymal stem cells have been tested in several clinical studies, but their beneficial effect still remains controversial. In this review, we would like to overview the recent clinical challenges of stem cell-based therapies in IBD and also introduce our new therapeutic plan of intestinal stem cell transplantation for IBD, based on our ex vivo intestinal organoid culture technique.

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IBD

Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn’s disease in Asia: Choon Jin Ooi, Ida Hilmi, Rupa Banerjee, Sai Wei Chuah, Siew Chien Ng, Shu Chen Wei, Govind K Makharia, Pises Pisespongsa, Min Hu Chen, Zhi Hua Ran, Byong Duk Ye, Dong Il Park, Khoon Lin Ling, David Ong, Vineet Ahuja, Khean Lee Goh, Jose Sollano, Wee Chian Lim, Wai Keung Leung, Raja Affendi Raja Ali, Deng Chyang Wu, Evan Ong, Nazri Mustaffa, Julajak Limsrivilai, Tadakazu Hisamatsu, Suk Kyun Yang, Qin Ouyang, Richard Geary, Janaka H De Silva, Rungsun Rerknimitr, Marcellus Simadibrata, Murdani Abdullah, Rupert WL Leong, the Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for Crohn’s and Colitis; Intest Res 2019;17(3):285-310. Published online May 31, 2019; DOI: https://doi.org/10.5217/ir.2019.00026

Abstract PDF PubReader ePub

The Asia-Pacific Working Group on inflammatory bowel disease (IBD) was established in Cebu, Philippines, under the auspices of the Asian Pacific Association of Gastroenterology with the goal of improving IBD care in Asia. This consensus is carried out in collaboration with Asian Organization for Crohn’s and Colitis. With biologic agents and biosimilars becoming more established, it is necessary to conduct a review on existing literature and establish a consensus on when and how to introduce biologic agents and biosimilars in the conjunction with conventional treatments for ulcerative colitis (UC) and Crohn’s disease (CD) in Asia. These statements also address how pharmacogenetics influence the treatments of UC and CD and provide guidance on response monitoring and strategies to restore loss of response. Finally, the review includes statements on how to manage treatment alongside possible hepatitis B and tuberculosis infections, both common in Asia. These statements have been prepared and voted upon by members of IBD workgroup employing the modified Delphi process. These statements do not intend to be all-encompassing and future revisions are likely as new data continue to emerge.

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Epithelial-microbial diplomacy: escalating border tensions drive inflammation in inflammatory bowel disease: Stephanie J King, Declan F McCole; Intest Res 2019;17(2):177-191. Published online March 7, 2019; DOI: https://doi.org/10.5217/ir.2018.00170

Abstract PDF PubReader ePub

Inflammatory bowel diseases (IBD) are chronic conditions of the gastrointestinal tract-the main site of host-microbial interaction in the body. Development of IBD is not due to a single event but rather is a multifactorial process where a patient’s genetic background, behavioral habits, and environmental exposures contribute to disease pathogenesis. IBD patients exhibit alterations to gut bacterial populations “dysbiosis” due to the inflammatory microenvironment, however whether this alteration of the gut microbiota precedes inflammation has not been confirmed. Emerging evidence has highlighted the important role of gut microbes in developing measured immune responses and modulating other host responses such as metabolism. Much of the work on the gut microbiota has been correlative and there is an increasing need to understand the intimate relationship between host and microbe. In this review, we highlight how commensal and pathogenic bacteria interact with host intestinal epithelial cells and explore how altered microenvironments impact these connections.

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An overview of the role of exclusive enteral nutrition for complicated Crohn’s disease: Mustafa Adamji, Andrew S Day; Intest Res 2019;17(2):171-176. Published online December 3, 2018; DOI: https://doi.org/10.5217/ir.2018.00079

Abstract PDF PubReader ePub

The role and efficacy of exclusive enteral nutrition (EEN) in the treatment of luminal Crohn’s disease (CD) has been well established over the last 2 decades. Consequently, in many centers nutritional therapy is now considered first line therapy in the induction of remission of active CD. However, the use of nutritional therapy in complicated CD has yet to be fully determined. This article aimed to review case reports and clinical trials published in the last decade that have considered and evaluated nutritional therapy in the setting of complicated CD in children and adults. Published literature focusing upon the use of nutritional therapy as part of medical therapy in the management of complicated CD were identified and reviewed. Although there continue to be various interventions utilized for complicated CD, the currently available literature demonstrates that nutritional therapies, especially EEN, have important roles in the management of these complex scenarios. Further assessments, involving large numbers of patients managed with consistent approaches, are required to further substantiate these roles.

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Does fecal calprotectin equally and accurately measure disease activity in small bowel and large bowel Crohn’s disease?: a systematic review: Ebby George Simon, Richard Wardle, Aye Aye Thi, Jeanette Eldridge, Sunil Samuel, Gordon William Moran; Intest Res 2019;17(2):160-170. Published online February 7, 2019; DOI: https://doi.org/10.5217/ir.2018.00114

Abstract PDF Supplementary Material PubReader ePub

Fecal calprotectin (FC) is a highly sensitive disease activity biomarker in inflammatory bowel disease. However, there are conflicting reports on whether the diagnostic accuracy in Crohn’s disease is influenced by disease location. The aim of this study was to undertake a systematic review of the published literature. Relevant databases were searched from inception to November 8, 2016 for cohort and case control studies which had data on FC in patients with isolated small bowel (SB) and large bowel (LB) Crohn’s disease. Reference standards for disease activity were endoscopy, magnetic resonance imaging, computed tomography or a combination of these. The QUADAS-2 research tool was used to assess the risk of bias. There were 5,619 records identified at initial search. The 2,098 duplicates were removed and 3,521 records screened. Sixty-one full text articles were assessed for eligibility and 16 studies were included in the final review with sensitivities and specificities per disease location available from 8 studies. Sensitivities of FC at SB and LB locations ranged from 42.9% to 100% and 66.7% to 100% respectively while corresponding specificities were 50% to 100% and 28.6% to 100% respectively. The sensitivities and specificities of FC to accurately measure disease activity in Crohn’s disease at different disease locations are diverse and no firm conclusion can be made. Better studies need to be undertaken to categorically answer the effect of disease location on the diagnostic accuracy of FC.

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Digestive Diseases and Sciences.2024; 69(8): 2955. CrossRef
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Gastroenterology.2023; 165(6): 1367. CrossRef
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Analytical Chemistry.2023; 95(50): 18564. CrossRef
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Gut and Liver.2022; 16(1): 62. CrossRef
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Improving the quality of care for inflammatory bowel disease: Byong Duk Ye, Simon Travis; Intest Res 2019;17(1):45-53. Published online November 20, 2018; DOI: https://doi.org/10.5217/ir.2018.00113

Abstract PDF PubReader ePub

Great strides have been achieved in the development of quality-of-care measures and standards for inflammatory bowel disease (IBD) over the last decade. The central structural component of care in IBD revolves around the multidisciplinary team, which should be equipped with the necessary resources to operate and implement decisions. Process measures have been defined by interest groups and can be adapted into process tools for the delivery of care for various patient subgroups and clinical scenarios. The emerging treat-to-target approach to IBD management may be used to achieve optimal long-term and holistic patient-centred outcomes, such as survival, control of inflammation and disease progression, symptomatic remission, quality of life and complications. Other important quality-of-care outcome measures for IBD include disutility of care, healthcare utilization and other patient-reported outcomes such as nutritional status and impact of fistulae. The current challenge for healthcare providers and health systems is the integration of quality-of-care structures and processes into clinical practice, and the consistent delivery of updated evidence-based quality IBD care to various patient populations by individual health care providers. Finally, the awareness and appreciation for quality of care in IBD is increasing in Asia, and Asian healthcare institutions should be encouraged to take the lead in improving the quality of care in IBD.

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Alimentary Pharmacology & Therapeutics.2019; 50(2): 176. CrossRef

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Current new challenges in the management of ulcerative colitis: Tomohiro Fukuda, Makoto Naganuma, Takanori Kanai; Intest Res 2019;17(1):36-44. Published online January 25, 2019; DOI: https://doi.org/10.5217/ir.2018.00126

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Ulcerative colitis (UC) is a chronic inflammatory condition of the gastrointestinal tract. Although the cause of UC is postulated to be multifactorial in nature, including genetic predisposition, epithelial barrier defects, dysregulation of immune responses, and environmental factors, the specific pathogenesis of UC is still incompletely understood. In the treatment of UC so far, a method of suppressing immunity and treating it has been mainstream. Immunosuppressant drugs, including thiopurines (azathioprine or 6-mercaptopurine), anti-tumor necrosis factor-α (anti-TNF-α) antibody (infliximab and adalimumab), and calcineurin inhibitor, can be used in treat patients with corticosteroid-dependent and/or corticosteroid-refractory moderateto- severe UC. Recently, in addition to such a conventional therapeutic agent, golimumab, which is the first transgenic human monoclonal anti-TNF-α antibody to be fabricated, anti α-4/β-7 integrin antibody, and Janus kinase inhibitor have been reported to novel immunosuppressant therapy. Furthermore, other treatments with unique mechanisms different from immunosuppression, have also been suggested, including fecal microbiota transplantation and Indigo naturalis, which is a Chinese herbal medicine. We compared the features and efficacy of these new treatments. In this issue, the features and treatment options for these new treatments is reviewed.

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Alimentary Pharmacology & Therapeutics.2024; 60(5): 563. CrossRef
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Canadian Journal of Microbiology.2023; 69(4): 158. CrossRef
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Intestinal Research.2023; 21(2): 174. CrossRef
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BMC Gastroenterology.2022;[Epub] CrossRef
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Gut and Liver.2022; 16(4): 567. CrossRef
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Journal of Nanobiotechnology.2022;[Epub] CrossRef
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The Korean Journal of Internal Medicine.2022; 37(5): 949. CrossRef
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