Pseudo-Obstruction of Jejunum due to AA Amyloidosis Associated with Latent Syphilis |
Young Hwangbo, Hyo Jong Kim, Jae Yeon Lee, Jae Young Jang, Seok Ho Dong, Byung Ho Kim, Young Woon Chang, Rin Chang |
Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea
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공장의 가성폐쇄를 동반한 잠복매독에 의한 AA형 아밀로이드증 1예 |
황보영, 김효종, 이재연, 장재영, 동석호, 김병호, 장영운, 장린 |
경희대학교 의과대학 내과학교실 |
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Abstract |
Amyloidosis uncommonly presents with intestinal pseudo-obstruction. According to previous reports, patients with primary AL amyloidosis presented with a chronic process with symtom duration of more than 1 year, but patients with secondary AA amyloidosis presented as an acute illness, usually less than 10 weeks. Localized gastrointestinal amyloidosis limited to the jejunum, without involvement of stomach, duodenum, colon, or rectum, is very rare. Imaging studies in small intestinal amyloidosis generally show a symmetrical uniform appearance. AA amyloidosis with acute-phase reactant serum amyloid A protein is associated with inflammatory, infectious or neoplastic disorders. To our knowledge, no case of amyloidosis associated with latent syphilis has been reported to date. We present a case of a 56-year-old man who presented with clinical and radiographic features of a small bowel obstruction and obscure gastrointestinal bleeding. Investigations including laparoscopy and other laboratory dataled to a diagnosis of pseudo-obstruction of the jejunum due to AA amyloidosis associated with latent syphilis. After appropriate treatment for latent syphilis, abdominal symptoms had been disappeared, but jejunal dilatation was still present two years later. (Intest Res 2010;8:195-199) |
Key Words:
Amyloidosis, Syphilis, Intestinal Pseudo-Obstruction, Jejunum |
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