Comparison of Bowel Preparation Depending on Completion Time of Polyethylene Glycol Ingestion and Start Time of Colonoscopy

Yoon, Jang Hyuk; Park, Dong Il; Shin, Jeong Eun; Kim, Seong Eun; Jung, Sung Ae; Lee, Suck Ho; Chang, Dong Kyung; Eun, Chang Soo; Han, Dong Soo; Kim, Hyun Soo; Park, Seun Ja; Baek, Il Hyun; Keum, Bora; Jeen, Yoon Tae

doi:2010.8.1.24

Intest Res > Volume 8(1); 2010 > Article

Original Article

Intestinal Research 2010;8(1):24-29.
DOI: https://doi.org/10.5217/ir.2010.8.1.24 Published online June 30, 2010.

Comparison of Bowel Preparation Depending on Completion Time of Polyethylene Glycol Ingestion and Start Time of Colonoscopy

Jang Hyuk Yoon, Dong Il Park, Jeong Eun Shin, Seong Eun Kim, Sung Ae Jung, Suck Ho Lee, Dong Kyung Chang, Chang Soo Eun, Dong Soo Han, Hyun Soo Kim, Seun Ja Park, Il Hyun Baek, Bora Keum, Yoon Tae Jeen

^*Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine
^†Seoul, Dankook University College of Medicine
^‡Cheonan, Ewha Womans University School of Medicine
^§Seoul, Soonchunhyang University College of Medicine
^∥Cheonan, Samsung Seoul Hospital, Sungkyunkwan University College of Medicine∥
^¶Seoul, Hanyang University College of Medicine
^**Seoul, Yonsei University Wonju College of Medicine
^††Wonju, Koshin University College of Medicine
^‡‡Busan, Hallym University College of Medicine
^§§Seoul, Yeungnam University College of Medicine
^∥∥Daegu, Korea University College of Medicine, Seoul, Korea

Polyethylene Glycol 용액의 복용완료시간과 대장내시경 검사시작 시간에 따른 대장 정결도의 비교

윤장혁, 박동일, 신정은†, 김성은, 정성애, 이석호, 장동경, 은창수, 한동수, 김현수, 박선자, 백일현, 장병익, 금보라

^*성균관대학교 의과대학 강북삼성병원 내과학교실
^†단국대학교 의과대학 내과학교실
^‡이화여자대학교 의과대학 내과학교실
^§순천향대학교 의과대학 내과학교실
^∥성균관대학교 의과대학 삼성서울병원 내과학교실
^¶한양대학교 의과대학 내과학교실
^**연세대학교 원주의과대학 내과학교실
^††고신대학교 의과대학 내과학교실
^‡‡한림대학교 의과대학 내과학교실
^§§영남대학교 의과대학 내과학교실
^∥∥고려대학교 의과대학 내과학교실

Abstract

Background/Aims
Polyethylene glycol (PEG) solution is the most widely used bowel preparation agent for colonoscopy because of its safety and efficacy in colon cleansing. It has been hypothesized that the timing of colon preparation may influence the quality of colon cleansing, and therefore affect the diagnostic yield of colonoscopy. The aim of this study was to determine the optimal interval of time between complete ingestion of PEG and performing colonoscopy. Methods: We prospectively enrolled 1,355 patients who had undergone a PEG-based bowel preparation on the day of colonoscopy in 11 tertiary hospitals in Korea between March 2008 and February 2009. All colonoscopies were performed in the afternoon. The start time of PEG ingestion, completion time of PEG ingestion, dose of PEG ingested, start time of colonoscopy, and the quality of bowel cleansing were recorded. Results: There was no difference of cleansing quality of bowel preparation between three groups of less than 7 hours of elapsed time (2≤ and <3 hours, 3≤ and <5 hours, 5≤ and <7 hours). However, group of more than 7 hours of elapsed time presented poor cleansing quality than others (P<0.01). Conclusions: If >7 hours elapses after ingestion of PEG, the quality of bowel preparation is poor. Therefore, depending on the time colonoscopy is scheduled, the start time of PEG ingestion may need to be adjusted. (Intest Res 2010;8:24-29)

Key Words: Colonoscopy, Polyethylene Glycol (PEG) Solution, Bowel Preparation