Intest Res 2018; 16(3): 494-498  https://doi.org/10.5217/ir.2018.16.3.494
Effect of elemental diet combined with infliximab dose escalation in patients with Crohn’s disease with loss of response to infliximab: CERISIER trial
Tadakazu Hisamatsu1*, Reiko Kunisaki2*, Shiro Nakamura3, Tomoyuki Tsujikawa4, Fumihito Hirai5, Hiroshi Nakase6, Kenji Watanabe7,8, Kaoru Yokoyama9, Masakazu Nagahori10, Takanori Kanai11, Makoto Naganuma11, Hirofumi Michimae12, Akira Andoh13, Akihiro Yamada14, Tadashi Yokoyama15, Noriko Kamata16, Shinji Tanaka17, Yasuo Suzuki14, Toshifumi Hibi18, Mamoru Watanabe10, CERISIER Trial group#
1The Third Department of Internal Medicine, Kyorin University School of Medicine, Mitaka, 2Inflammatory Bowel Disease Center, Yokohama City University Medical Center, Yokohama, 3Department of Inflammatory Bowel Disease, Hyogo College of Medicine, Nishinomiya, 4Department of Gastroenterology and Hepatology, National Hospital Organization, Higashi-Ohmi Medical Center, Higashi-Ohmi, 5Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, 6Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, 7Division of Gastroenterology, Osaka City General Hospital, Osaka, 8Department of Intestinal Inflammation Research, Hyogo College of Medicine, Nishinomiya, 9Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, 10Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, 11Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, 12Department of Clinical Medicine (Biostatistics), Kitasato University School of Pharmacy, Tokyo, 13Division of Gastroenterology, Shiga University of Medical Science, Otsu, 14Department of Internal Medicine, Toho University Sakura Medical Centre, Sakura, 15Yokoyama IBD Clinic, Aichi, 16Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, 17Department of Endoscopy, Hiroshima University Hospital, Hiroshima, 18Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan
Correspondence to: Tadakazu Hisamatsu, Division of Gastroenterology and Hepatology, The Third Department of Internal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka 181-8611, Japan. Tel: +81-422-47-5511 (ext. 5729), Fax: +81-422-71-5381, E-mail: thisamatsu@ks.kyorin-u.ac.jp
*These authors contributed equally to this study.
#Combination of Elemental Dietary Therapy and Infliximab for Secondary Failure to Infliximab in Patients with Crohn’s Disease (CERISIER) Trial group members: Hideaki Kimura2 , Shingo Kato19, Shigeki Bamba13, Yuji Naito20, Takuya Inoue21, Shuhei Hosomi16, Masaki Iimuro3 , Akira Harada22, Takahiro Beppu5
19Department of Gastroenterology and Hepatology, Saitama Medical Centre, Saitama Medical University, Kawagoe, 20Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 212nd Department of Internal Medicine, Osaka Medical College, Takatsuki, 22Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan
Received: October 23, 2017; Revised: December 29, 2017; Accepted: January 9, 2018; Published online: July 30, 2018.
© Korean Association for the Study of Intestinal Diseases. All rights reserved.

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