Intestinal Research 2017; 15(3): 285-310  
Management of Crohn’s disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease
Shu-Chen Wei1, Ting-An Chang2, Te-Hsin Chao3, Jinn-Shiun Chen4, Jen-Wei Chou5, Yenn-Hwei Chou6, Chiao-Hsiung Chuang7, Wen-Hung Hsu8, Tien-Yu Huang9, Tzu-Chi Hsu10, Chun-Chi Lin11, Hung-Hsin Lin11,12, Jen-Kou Lin11, Wei-Chen Lin13, Yen-Hsuan Ni14, Ming-Jium Shieh15, I-Lun Shih16, Chia-Tung Shun17, Yuk-Ming Tsang18, Cheng-Yi Wang1, Horng-Yuan Wang19,20,21, Meng-Tzu Weng22, Deng-Chyang Wu23,24, Wen-Chieh Wu25, Hsu-Heng Yen26, Jau-Min Wong1
1Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, 2Department of Pathology, Taipei City Hospital Renai Branch, Taipei, 3Division of Colorectal Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, 4Division of Colorectal Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, 5Division of Gastroenterology and Hepatology, Department of Internal Medicine, China Medical University Hospital, Taichung, 6Division of General Surgery, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, 7Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University College of Medicine, Tainan, 8Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Municipal Hsiaokang Hospital, Kaohsiung, 9Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, 10Division of Colon and Rectal Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei, 11Division of Colon and Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, 12Department of Surgery, National Yang-Ming University, Taipei, 13Department of Internal Medicine, Mackay Memorial Hospital, Taipei, 14Department of Pediatrics, National Taiwan University Hospital, Taipei, Departments of 15Oncology, 16Medical Imaging, and 17Pathology and Forensic Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, 18Division of Medical Imaging, Department of Radiology, Far Eastern Memorial Hospital, New Taipei City, 19Division of Gastroenterology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, 20MacKay Junior College of Medicine, Nursing, and Management, Taipei, 21MacKay Medical College, New Taipei City, 22Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, 23Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 24Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, 25Division of Gastroenterology, Department of Medicine, Taipei City Hospital Renai Branch, Taipei, 26Division of Gastroenterology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan
Correspondence to:
Jau-Min Wong, Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No.7 Chung-Shan South Road, Taipei 101, Taiwan. Tel: +886-2-23123156, Fax: +886-2-23940049, E-mail: jmwong@ntu.edu.tw
Received: March 13, 2017; Revised: May 2, 2017; Accepted: May 2, 2017; Published online: July 30, 2017.
© Korean Association for the Study of Intestinal Diseases. All rights reserved.

Abstract
Crohn’s disease (CD) is a chronic relapsing and remitting inflammatory disease of the gastrointestinal tract. CD is rare in Taiwan and other Asian countries, but its prevalence and incidence have been steadily increasing. A steering committee was established by the Taiwan Society of Inflammatory Bowel Disease to formulate statements on the diagnosis and management of CD taking into account currently available evidence and the expert opinion of the committee. Thorough clinical, endoscopic, and histological assessments are required for accurate diagnosis of CD. Computed tomography and magnetic resonance imaging are complementary to endoscopic evaluation for disease staging and detecting complications. The goals of CD management are to induce and maintain remission, reduce the risk of complications, and improve quality of life. Corticosteroids are the mainstay for inducing re-mission. Immunomodulating and biologic therapies should be used to maintain remission. Patients should be evaluated for hepatitis B virus and tuberculosis infection prior to treatment and receive regular surveillance for cancer. These consensus statements are based on current local evidence with consideration of factors, and could be serve as concise and practical guidelines for supporting clinicians in the management of patients with CD in Taiwan. (Intest Res 2017;15:285-310)
Keywords: Taiwan; Crohn disease; Inflammatory bowel diseases; Disease management; Consensus statements


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