Intest Res  
Coexistence of ulcerative colitis and Sjögren’s syndrome in a patient with Takayasu’s arteritis and Hashimoto’s thyroiditis
Hyun Woo Park1, Hyun Seok Lee1, Sejin Hwang1, Han Sol Lee1, Han-Ik Bae2, Ghilsuk Yoon2
1Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, 2Department of Pathology, Kyungpook NationalUniversity School of Medicine, Daegu, Korea
Correspondence to: Hyun Seok Lee, Department of Internal Medicine, Kyungpook National University Medical Center, Kyungpook National University School of Medicine, 807 Hoguk-ro, Buk-gu, Daegu 41404, Korea.
Tel: +82-53-200-2603, Fax: +82-53-200-2027, E-mail: lhsworld@nate.com
Received: November 11, 2015; Revised: February 1, 2016; Accepted: March 11, 2016; Published online: March 7, 2017.
© Korean Association for the Study of Intestinal Diseases. All rights reserved.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
A 31-year-old woman with a 15-year history of Takayasu’s arteritis (TA) and a 13-year history of Hashimoto’s thyroiditis presented with hematochezia. She received a diagnosis of Sjögren’s syndrome at 1 month before her visit to Kyungpook National University Medical Center. Her colonoscopic findings were compatible with a diagnosis of ulcerative colitis (UC). She was treated with oral mesalazine, and her hematochezia symptoms subsequently disappeared. The coexistence of UC and TA has been reported; however, reports on the coexistence of UC and Sjögren’s syndrome, or of UC and Hashimoto’s thyroiditis are rare. Although the precise etiologies of these diseases are unknown, their presence together suggests that they may have a common pathophysiologic background. Furthermore, in patients with autoimmune or vascular diseases, including TA, systemic manifestations should be assessed with consideration of inflammatory bowel diseases including UC in the presence of gastrointestinal symptoms such as diarrhea and hematochezia.
Keywords: Takayasu arteritis; Colitis, ulcerative; Sjogren’s syndrome; Hashimoto disease


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